raves’ ophthalmopathy (GO) is an inflammatory process that affects tissues of the orbit in patients with Graves’ disease (GD) and, more rarely, with Hashimoto’s thyroiditis. It is the most frequent extrathyroidal manifestation of Graves’ disease. GO is a disfi guring disease that impairs, even in its milder forms, the quality of life of affected patients. It is clinically signifi cant in 50% of...

The purpose of the research was to formulate microspheres of acyclovir (ACV) using mucoadhesive polymers, sodium alginate and chitosan. Calcium chloride was used as the ionotropic gelling agent. Sodium alginate was crosslinked by calcium chloride leading to a slower release of the drug. Chitosan which is a cationic polymer interacted with sodium alginate, an anionic polymer, to form an interpol...

Dilute aqueous solutions of Rhodium (III) at the Cl~/Rh(III) ratios 4.86 and 10.7 have been X-ray examined. Octahedral R h ( H 2 0 ) ^ + and Rh(H 2 0) 3 Cl 3 complexes are the species which are consistent with the correlation functions and the structure functions. The average number of bonded chloride ions per Rhodium atom has been determined and the reliability of the structural information is...

In the title compound, [Rh(C(22)H(32)N(3)O(5))(CO)(2)], the Rh(I) atom is coordinated by two carbonyl ligands and two tropolonate O atoms in a distorted square-planar geometry. It is an example of a new type of tropolone derivative that has not been characterized via solid-state methods. Weak intra-molecular C-H⋯N and inter-molecular C-H⋯O hydrogen bonds, and π-π stacking inter-actions between ...

The biosynthesis of [NiFe] hydrogenases is a complex process that requires the function of the Hyp proteins HypA, HypB, HypC, HypD, HypE, HypF, and HypX for assembly of the H(2)-activating [NiFe] site. In this study we examined the maturation of the regulatory hydrogenase (RH) of Ralstonia eutropha. The RH is a H(2)-sensing [NiFe] hydrogenase and is required as a constituent of a signal transdu...

The spatial heterogeneity of stomatal closure in response to rapid desiccation of excised well-watered Tradescantia virginiana leaves grown at moderate (55%) or high (90%) relative air humidity (RH) was studied using a chlorophyll fluorescence imaging system under non-photorespiratory conditions. Following rapid desiccation, excised leaves grown at high RH had both a greater heterogeneity and a...

Rhesus (Rh) protein involvement in ammonia transport processes in freshwater fish has received considerable attention; however, parallel investigations in seawater species are scant. We exposed pufferfish to high environmental ammonia (HEA; 1 and 5 mmol l(-1) NH(4)HCO(3)) and evaluated the patterns of ammonia excretion and gill Rh mRNA and protein expression. Gill H(+)-ATPase, NHE1, NHE2, NHE3,...

The catalytic hydrogenation of halonitroarenes to haloanilines is a green and sustainable process for the production key nitrogen-containing intermediates in fine chemical industry. Chemoselective poses significant challenge, which requires rational design catalysts with proper ability nitro group simultaneously preventing dehalogenation halogen group. Herein, highly effective Rh@Al 2 O 3 @C si...