69 INTRODUCTION It has been estimated that more than 1 million deer-vehicle crashes (DVCs) occur each year in the United States, costing the traveling public more than $1 billion.1 Some of the countermeasures that have been applied to reduce DVCs include deer fencing, wildlife crossing structures, roadside reflectors, vehicle whistles, highway lighting and speed limit reductions.2–4 The install...

BACKGROUND Uveitis is an eye inflammatory disease, which is sometimes associated with underlying systemic disease. Interleukin-23 plays an important role in autoimmune disease. The aim of this meta-analysis was to evaluate the association between the interleukin-23 receptor (IL-23R) and susceptibility to uveitis. METHODS Published literature from PUBMED and EMBASE were retrieved. Seven studie...

George Palade's pioneering work in the 1960s had established the secretory pathway and its connection to the biogenesis of organelles as a major theme in eukary-otic cell biology (Palade, 1975). His disciples, including David Sabatini and Gunter Blobel, extended Palade's morphological approaches to the next level of analysis, involving subcellular fractionation and biochemical re-constitution t...