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OBJECTIVE To identify the role of institution and surgeon factors, including case volume and experience, on survival of neonates with complex congenital heart disease. METHODS A total of 2421 neonates from 4 groups-transposition of the great arteries (n = 829), pulmonary atresia with intact ventricular septum (n = 408), Norwood (n = 710), and interrupted aortic arch (n = 474)-were prospective...
BACKGROUND The effectiveness of liver transplant (LT) in human immunodeficiency virus (HIV) and HIV/hepatitis C virus (HCV) coinfected recipients in the United States is unknown. We investigated (i) the effect of HIV on US patient and allograft LT outcomes, compared to HCV+ and HIV/HCV uninfected recipients and (ii) whether LT at centers that participated in the National Institutes of Health (N...
BACKGROUND Sensitive and easy-to-perform methods for the diagnosis of malaria are not yet available. Improving the limit of detection and following the requirements for certification are issues to be addressed in both endemic and non-endemic settings. The aim of this study was to test whether loop-mediated isothermal amplification of DNA (LAMP) may be an alternative to microscopy or real-time P...
Abstract Introduction ECGs are a NICE recommended pre-operative investigation and an integral part of post-operative monitoring. Delay in recognition cardiac pathology can be catastrophic. Therefore, ECG machines should readily available. Here, we report the results audit assessing availability surgical wards. Method In 2018 then 2020, bespoke, nine-item proforma was disseminated to all foundat...
BACKGROUND Visual inspection with acetic acid (VIA) to identify and treat pre-cancerous lesions is effective for cervical cancer prevention. Screening programs also facilitate screening and diagnosis of invasive cancers that must be referred for radiation therapy or chemotherapy. This study compared characteristics of women diagnosed with invasive cervical cancer by a VIA screening program who ...
RATIONALE Developmental patterns of lung function during childhood may have major implications for our understanding of the pathogenesis of respiratory disease throughout life. OBJECTIVES To explore longitudinal trajectories of lung function during childhood and factors associated with lung function decline. METHODS In a population-based birth cohort, specific airway resistance (sRaw) was a...
BACKGROUND/AIMS Recent studies have demonstrated marked renin and prorenin concentration gradients between ocular tissues and blood, and local expression of the renin-angiotensin system (RAS) in the eye. The authors determined whether serum total renin, which mostly consists of prorenin, is a marker of the activity and severity of diabetic retinopathy independent of other microvascular complica...
BACKGROUND Preconception and pregnancy dietary intakes can influence the health of future generations. In this study we compared the food intakes of reproductive-aged women by pregnancy status, to current Australian recommendations. METHODS Data are from the Australian Longitudinal Study on Women's Health, younger cohort aged 25-30 years in 2003, with self-reported status as pregnant (n = 606...
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