B. Szegedy [Edge coloring models and reflection positivity, Journal of the American Mathematical Society 20 (2007) 969–988] showed that the number of homomorphisms into a weighted graph is equal to the partition function of a complex edge-coloring model. Using some results in geometric invariant theory, we characterize for which weighted graphs the edge-coloring model can be taken to be real va...

Metal–oxide–semiconductor field-effect transistors ~MOSFETs! with a wire-channel and wrap-around-gate ~WW! structure were fabricated using electron beam lithography and reactive ion etching. The smallest devices have a 35 nm channel width, a 50 nm channel thickness, and a 70 nm channel length. Measurements showed that as the channel width of WW MOSFETs decreased from 75 to 35 nm short channel e...

Shrinking budgets and increased fiscal accountability mean that management needs a sound financial justification before committing funds to software process improvements such as Software Performance Engineering (SPE). Preparing a business case for SPE can demonstrate that the commitment is financially worthwhile and win support for an SPE initiative. This paper presents an introduction to the u...

Somatic mutations reported in large-scale breast cancer (BC) sequencing studies primarily consist of protein coding mutations. mRNA splicing mutation analyses have been limited in scope, despite their prevalence in Mendelian genetic disorders. We predicted splicing mutations in 442 BC tumour and matched normal exomes from The Cancer Genome Atlas Consortium (TCGA). These splicing defects were va...

Expression vectors normally contain sequences that stimulate polyadenylation of the expressed mRNA. These sequences usually include an AATAAA consensus sequence 20-30 nucleotides 5' of a diffuse GTor T-rich stretch immediately following the sequences that form the 3' end of the mRNA. The efficiency of the two minimal elements is also influenced by additional upor downstream elements (1). Very o...

Performance antipatterns document common software performance problems as well as their solutions. These problems are often introduced during the architectural or design phases of software development, but not detected until later in testing or deployment. Solutions usually require software changes as opposed to system tuning changes. This paper presents three new performance antipatterns and g...

Scalability is one of the most important quality attributes of today’s software systems. Yet, despite its importance, scalability in applications is poorly understood. This paper presents a model-based view of scalability in Web and other distributed applications that is aimed at removing some of the myth and mystery surrounding this important software quality. We review four models of scalabil...

9 The effect of mixer shear strain rate on the performance of a model 10 micro-crystalline cellulose pharmaceutical paste undergoing extru11 sion–spheronisation was studied using a laboratory scale planetary 12 mixer and a screw-based mixer. The maximum shear strain rate in 13 each mixer was estimated. Five pastes were prepared, one each at 14 97 and 265 s−1 in the planetary mixer, and one each...

| October 2012 | 988 L e t t e r t o e d it o r • If possible, prepare a cool pack to store insulin. • Prepare glucose and ketone dipsticks (to know the state of diabetes control during Ihram). • Choose shoes, sandals and flip flops with appropriate shape and size (front of shoes should be wide enough to avoid extra pressure on your feet and toes during long walking). • Pack your medications in...

Researching effects of media and advertising demands a search for a cost efficient, quick and verified method of testing the its emotional as well as rational effects on consumers. Thus a CASC (Communication Analytic and Syncretic Cognitions) scale was developed to meassure advertising effects and was selected for testing. In an extended research presented in this paper and based on 988 respond...