Phosphorylation of tau protein at Ser-262 has been shown to diminish its ability to bind to taxol-stabilized microtubules. The paired helical filaments (PHFs) found in Alzheimer's disease brain are composed of PHF-tau, which is hyperphosphorylated at multiple sites including Ser-262. However, protein kinase(s) able to phosphorylate this site are still under investigation. In this study, the abi...

This study carried out to investigate the production of hydrogen using the organic fraction of municipal solid waste OFMSW, where the anaerobic digester was depended as a method for disposing and treating OFMSW and producing bio-hydrogen. Bio-hydrogen production had been studied under different parameters including pH, solid content T.S%, temperature and mixing ratios between the thick sludge t...

http://ajs.sagepub.com/content/41/2/356 The online version of this article can be found at: DOI: 10.1177/0363546512471299 2013 41: 356 originally published online January 8, 2013 Am J Sports Med Sandeep Patel, Mandeep S. Dhillon, Sameer Aggarwal, Neelam Marwaha and Ashish Jain Prospective, Double-Blind, Randomized Trial Treatment With Platelet-Rich Plasma Is More Effective Than Placebo for Knee...

BackgroundChronic total occlusion (CTO) recanalization remains one of the most challenging procedures in interventional cardiology, and inability to cross lesion with a guidewire is common cause CTO percutaneous coronary intervention (PCI) failure. While current standard evaluation mostly based on anatomical complexity scores, global comprehensive approach could help guiding clinical decision a...

BACKGROUND The purpose of this study was to evaluate the clinical outcome in patients with benign parotid gland tumors after extracapsular dissection or superficial parotidectomy (SP). METHODS Eight hundred ninety-four patients with primary pleomorphic adenoma or Warthin's tumor were included from this study. Type and length of surgery, tumor size, resection margins, and complication rates we...

We explore two predictive tasks: (i) a measure of tag probability, and (ii) identifying a minimum tag set for more meaningful music classification on a 100,000 song dataset joined across complementary databases from the 1 Million Song Dataset (“MSD”). We conclude that a tag set size of around 50 tags is most meaningful and report many of our findings/analysis based on the top 50 tags. Using lin...

In the present work we model a Multiquantum Well structure Separate Absorption and Charge Multiplication Avalanche Photodiode (MQW-SACM-APD), while the Absorption region coincide with the MQW. We consider the nonuniformity of electric field using split-step method in active region. This model is based on the carrier rate equations in the different regions of the device. Using the model we obtai...