Donor shortage remains the single most important factor limiting the success of transplantation medicine. In face of this unrelenting pressure, otherwise prohibitive immunological barriers are increasingly accepted, such as ABO incompatibility of a kidney from an available living donor. Treatment protocols for such situations involve varying combinations of B-cell depletion, removal of isohemag...

Abstract Objective The history of the studies on blood groups dates back to early 20th century. More than 600 antigenic structures were detected among 29 blood groups. However, ABO and Rh antigenic structures were taken into consideration in transfusion medicine. Frequency of the blood groups in a community helps the individuals in need and blood bank employees, which could be related to some...

OBJECTIVE The aim of the study was to determine blood groups and Rhesus factor from dentin and pulp using absorption-elution (AE) technique in different time periods at 0, 3, 6, 9 and 12 months, respectively. MATERIALS AND METHODS A total of 150 cases, 30 patients each at 0, 3, 6, 9 and 12 months were included in the study. The samples consisted of males and females with age ranging 13-60 yea...

BACKGROUND ABO blood type incompatibility between a donor and recipient is generally considered a contraindication to kidney transplantation. CASE CHARACTERISTICS A 12-year-old boy presented with end stage renal disease (blood group B), with the only healthy available donor being mother (blood group AB). The child received renal transplant with mother as the donor, with a designed desensitiza...

blood samples (291857) from 24 provinces of iran were tested for abo and rh groups. the rh complexes as well as kell, duffy, kidd, lutheran, kp and xg blood groups were tested only on a part of the material from tehran. results show a great deal of heterogeneity for abo and rh groups in various provinces of iran. the calculated gene frequencies are compared with those of other investigations in...

There are three common alleles (A, B, and O) at the human ABO blood group locus. We compared nucleotide sequences of these alleles, and relatively large numbers of nucleotide differences were found among them. These differences correspond to the divergence time of at least a few million years, which is unusually large for a human allelic divergence under neutral evolution. We constructed phylog...

The ABO histo-blood group, first discovered over a century ago, is found not only in humans but also in many other primate species, with the same genetic variants maintained for at least 20 million years. Polymorphisms in ABO have been associated with susceptibility to a large number of human diseases, from gastric cancers to immune or artery diseases, but the adaptive phenotypes to which the p...

Pediatricians have long argued that children are not little adults, and it seems intuitive that clinical practices and regulations should follow appropriately from this paradigm. One can find no better evidence to support this contention than the report by Almond et al1 published in this issue of Circulation. ABO incompatibility has been considered a relative or, by United Network for Organ Sha...

ABO genotyping is commonly used in several situations, including blood transfusion, personal identification and disease detection. The present study developed a novel method for ABO genotyping, using loop‑mediated isothermal amplification (LAMP). This method allows the simultaneous determination of six ABO genotypes under 40 min at a constant temperature of 62˚C. The genotypes of 101 blood samp...