Background: Various studies have tested quality of life (QOL) among drug addicts, however very few have reported any association between oral health-related quality of life (OHRQOL) and mode of drug administration among drug addicts. Hence, the present study was conducted aiming to evaluate the impact of mode of administration of drugs on OHRQOL among drug addicts. Methods: Data was collected u...

The assessment procedure of new synthetic illicit drugs that are not documented in the UN treaty on psychotropic drugs was evaluated using a modified Electre model. Drugs were evaluated by an expert panel via the open Delphi approach, where the written score was discussed on 16 items, covering medical, health, legal, and criminalistic issues of the drugs. After this face-to-face discussion the ...

We describe a procedure for extracting weakly acidic, neutral, and basic drugs from urine by using a column of XAD-2 resin. Adsorptionof drugs from, 20 ml of urine buffered at pH 8.5 ± 0.5 at a controlled flow rate of 2.5 mI/mm was greater than 89% for all drugs tested except aspirin. On eluting the drugs tested with acetone and methanol/chloroform, recoveries ranged from 75 to 93%. Overall rec...

Overtime, oral contraceptives has been used as an option for prevention of pregnancy due to their synthetic hormones composition that prevents fertilization. Regardless usefulness in contraception, studies have shown when these drugs are abused, they could cause some adverse effects the normal body metabolism. This study investigated Exluton and Combination-3 on serum Electrolyte (Sodium; Na+, ...

A point mutation in the aldehyde dehydrogenase 2 gene (ALDH2(2) allele) is considered to be a genetic deterrent for alcoholism; however, 80 of 655 Japanese alcoholics had the mutant allele. Genotype factors that might increase susceptibility by overriding the deterrent showed a higher frequency of a five repeat allele of the dopamine D4 receptor 48 bp repeat polymorphism in alcoholics with ALDH...

Sixty-nine opiate addicts on methadone maintenance programmes at the Drug Treatment Centre were interviewed, all meet DSM. 3 criteria for opioid dependency. Most were young, poorly educated, unemployed and had involvement with both police and prison. Drug abuse started at a young age, all had injected drugs, heroin being the most widely abused opiate. Forty-eight (70%) were HIV (Human Immunodef...

Buprenorphine is abused in several countries notwithstanding its benefits as an analgesic and opioid agonist treatment medication. Benzodiazepines alcohol have previously been associated with buprenorphine toxicity. This study elucidates the role of emerging concomitant drugs different groups user deaths. All cases Finnish national post-mortem toxicology database from 2016–2019 which or norbupr...