نتایج جستجو برای: accrual characteristic
تعداد نتایج: 177713 فیلتر نتایج به سال:
Selective serotonin-reuptake inhibitors (SSRIs) antagonize the serotonin (5-hydroxytryptamine) transporter (5-HTT), and are frequently prescribed to children and adolescents to treat depression. However, recent findings of functional serotonergic pathways in bone cells and preliminary clinical evidence demonstrating detrimental effects of SSRIs on bone growth have raised questions regarding the...
This study is the first to investigate: (a) 'temporal performance fields,' whether the speed of information accrual differs for different locations at a fixed eccentricity, and (b) whether covert attention modulates temporal dynamics differentially at isoeccentric locations. Using the speed accuracy tradeoff (SAT) procedure, we derived conjoint measures of how isoeccentric locations and precuei...
White matter signal abnormality (WMSA) is often present in the MRIs of older persons with mobility impairment. We examined the relationship between impaired mobility and the progressive accrual of WMSA. Mobility was assessed with the Short Physical Performance Battery (SPPB) and quantitative measures of gait and balance. Fourteen subjects had baseline and follow-up MRI scans performed 20 months...
Methods The trial recruits men with locally advanced or metastatic prostate cancer starting standard long-term hormone therapy. There are 5 research arms and 1 control arm. The trial has a pilot stage assessing safety and feasibility, 3 intermediate “activity” stages (I-III) where the outcome measure is failure-free survival (FFS) and one final “efficacy” stage (IV) with overall survival as pri...
OBJECTIVE To study damage accrual and mortality in British patients with SLE under long-term follow-up for >10 years. METHODS We analysed the clinical records of 232 patients with SLE who had at least 10 years of consistent follow-up at University College London Hospital (UCLH). We noted their SLICC/ACR Damage Index (SDI) scores and category of damage at 1 year post-diagnosis of SLE and every...
Successfully navigating a dynamic environment requires the efficient distribution of finite neural resources. Voluntary (endogenous) covert spatial attention selectively allocates those processing resources to goal-relevant locations in the visual scene in the absence of eye movements. However, the allocation of spatial attention is not always voluntary; abrupt onsets in the visual periphery au...
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