BH3-interacting domain death agonist (BID) is a crucial element in death signaling pathways and is recognized as an intracellular link connecting the intrinsic mitochondrial apoptotic and extrinsic death receptor-mediated apoptotic pathways. Herein, we describe experiments conducted with a fusion protein, which was generated by fusing a human epidermal growth factor receptor-2 (HER2)-specific s...

In part 21 of the tutorial series "Acoustofluidics--exploiting ultrasonic standing wave forces and acoustic streaming in microfluidic systems for cell and particle manipulation", we review applications of ultrasonic standing waves used for enhancing immunoassays and particle sensors. The paper covers ultrasonic enhancement of bead-based immuno-agglutination assays, bead-based immuno-fluorescenc...

Persistent hypocalcaemic tetany in a breast-fed neonate made us suspect DiGeorge's syndrome, particularly as the baby had an abnormal facies, and a ventricular septal defect. Immuno-reconstitution was successfully achieved by thymic transplant. Evidence of immuno-reconstitution on the basis of the histology of the post-transplant thymus has not been previously recorded.

Progressive Disseminated Histoplasmosis (PDH) is mainly described in immuno-compromised individuals and rare in immuno-competent subjects. Here we report a case of progressive disseminated histoplasmosis with Comb's positive hemolytic anemia, which is infrequently reported from a country like India where histoplasmosis is not an endemic mycosis.

We briefly outline an algorithm for accurate quantification of specific binding of gold particles to fixed biological tissue samples prepared for immuno-transmission electron microscopy (TEM). The algorithm is based on existing protocols for rational accounting of colloidal gold particles used in secondary antibodies for immuno-gold labeling.

The number of new Immuno-PCR technologies and applications is steadily growing as a result of a general need for more sensitive immunoassays for early detection of diseases. Although Immuno-PCR has been demonstrated to be superior to its immunoassay counterpart, it is still regarded as a challenging technology due to various problems arising from its increased detection power, such as high back...

Real-time PCR is a very sensitive technique to measure DNA concentrations. In real-time immuno-PCR, it is used as the detection system for quantification of proteins. Many ways to perform and assemble real-time immuno-PCR are possible. We have tested three different approaches for the detection of prostate specific antigen (PSA) and compared them with each other and with ELISA. We also demonstr...

Background & aimsAmino acids play an important role in immune responses and as neurotransmitters. During the course of a bacterial pneumonia episode, from onset to recovery phase, dramatically change, does metabolism amino acids, concept referred immuno-nutrition. We investigated differences plasma acid levels (PAA) between acute phases individuals with community-acquired (CAP) healthy controls...

HIV(Human Immunodeficiency Virus) adalah retrovirus yang menyerang limfosit T CD4 pada akhirnya menyebabkan kematian sel-sel. Acquired immuno deficiency syndrom (AIDS) disebabkan oleh virus HIV. Organisasi kesehatan dunia tahun 2020 menyatakan jumlah kasus baru HIV di seluruh hampir 1,5 juta 2020. Jumlah HIV/AIDS Indonesia ditemukan sebanyak 427.201 orang. Kasus NTB 2019 1.865 . Sebaran wilayah...

Due to a high risk and tendency of OPMDs towards OSCC, its early detection is essential for better survival rate. Several molecular markers are available diagnosis prognostic assessments OPMDs, also evaluating aggressiveness OSCC. Objectives: To assess the immuno-histochemical expression Cyclin D1 in normal healthy oral mucosa. has significant role cell cycle control strongly linked with metast...