BACKGROUND Limited data are available on the frequency of IgE mediated food sensitization and food allergy (FA) in adults with atopic dermatitis (AD). OBJECTIVE We investigated the pattern of food sensitization in adults with AD in relation to AD severity using multiplexed allergen microarray. METHODS 211 adult patients referred between January 2010-July 2011 for evaluation of AD were unsel...

We read with great interest the recent article by Teichmann et al. [1], who presented results of the Free and Cued Selective Reminding Test (FCSRT) accuracy to differentiate typical (amnestic) Alzheimer’s disease (AD) from other neurodegenerative diseases. The authors assessed FCSRT in a group of 992 individuals, most of them with the diagnosis of AD, and stated that FCSRT would have a sensitiv...

BACKGROUND The skin of atopic dermatitis (AD) patients has a high susceptibility to Staphylococcus aureus colonization, and the toxins produced by S. aureus may aggravate AD by acting as superantigens. OBJECTIVE The purpose of this study was to evaluate the relationship of the skin barrier function, colonization of S. aureus, and the clinical severity of AD. We also examined the predominant t...

Neuroimaging studies have demonstrated that patients with Alzheimer's disease presented disconnection syndrome. However, little is known about the alterations of interhemispheric functional interactions and underlying structural connectivity in the AD patients. In this study, we combined resting-state functional MRI and diffusion tensor imaging (DTI) to investigate interhemispheric functional a...

The diagnosis of idiopathic normal pressure hydrocephalus (iNPH) is sometimes complicated by concomitant Alzheimer's disease (AD) pathology. The purpose of the present study is to identify an iNPH-specific cerebrospinal fluid (CSF) biomarker dynamics and to assess its ability to differentiate iNPH from AD. Total tau (t-tau), tau phosphorylated at threonine 181 (p-tau), amyloid-β (Aβ) 42 and 40,...

OBJECTIVE Adjustment disorders (AD) are an ill-defined category in the present diagnostic nomenclature. We propose a new diagnostic model that describes AD as particular forms of stress response syndrome, in which intrusions, avoidance of reminders and failure to adapt are the central processes and symptoms. In line with the existing classification, the description of AD subtypes is included. B...

BACKGROUND AND PURPOSE AD has been documented as a kind of disconnection syndrome by functional neuroimaging studies. The primary focus of this study was to examine, with the use of resting-state fMRI, whether AD would impact connectivity among RSNs. MATERIALS AND METHODS Fourteen patients with AD and 16 NC were recruited and scanned by using resting-state fMRI. Group independent-component an...

The aim of this study is to show the cranial alterations that Klippel-Feil syndrome produced in a case older than 200 years. Few paleopathological studies diagnosed as Syndrome are focused on abnormalities. A skull numbered 778, belonging Federico Olóriz Aguilera collection (Spain, 19th century AD), Universidad Complutense de Madrid, young man born town North Spain, was investigated. This crani...