BACKGROUND The diagnosis of tuberculous meningitis (TBM) can be extremely difficult in the absence of culture confirmation. Cerebrospinal fluid (CSF) adenosine deaminase (ADA) can potentially assist in this regard, although its current value remains unclear. The literature on the usefulness of CSF ADA in TBM diagnosis is inconsistent, especially from an analytical point of view. METHODS A ret...

Adenosine deaminase (ADA), an enzyme essential for the differentiation of lymphoid cells, has been used for monitoring diseases with altered immunity. The purpose of this study was to investigate the changes in serum ADA activity throughout normal pregnancy. We measured the catalytic values of serum ADA from 202 normal pregnant women using a commercial kit. Subjects were divided into four group...

In this paper we investigate the interactions between artificial intelligence and Ada. The Ada language has been mandated for use in all U.S. Department of Defense mission critical embedded systems. Artificial intelligence has become an important ingredient in such systems. Currently, LISP is the language of choice among DoD AI implementors, and its continued use may retard the expected widespr...

Correspondence: HB Gaspar Molecular Immunology Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH Tel +44 207 905 2319 Fax +44 207 905 2810 email [email protected] Abstract: Adenosine deaminase deficiency (ADA) is a rare, inherited disorder of purine metabolism characterized by immunodeficiency, failure to thrive and metabolic abnormalities. A lack of the enzyme ADA a...

Four patients from 3 Saudi Arabian families had delayed onset of immune deficiency due to homozygosity for a novel intronic mutation, g.31701T>A, in the last splice acceptor site of the adenosine deaminase (ADA) gene. Aberrant splicing mutated the last 4 ADA amino acids and added a 43-residue "tail" that rendered the protein unstable. Mutant complementary DNA (cDNA) expressed in Escherichia col...

Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I-R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor-alpha (TNF-α) inhibitor agent. We aimed to evaluate whether Ada would prevent the lung tissue from damage development over the I-R process. Materials and Methods:Twenty seven Wistar albino male rats were divided into...

Background: In recent years, numerous regulators of gonadal function have been studied. Adenosine deaminase(ADA) is widely distributed throughout human tissues and may contribute in the regulation of menstrual cycle. The purpose of this study was to determine the plasma activities of total adenosine deaminase (ADAT), and its isoenzymes, ADA1 and ADA2, and ADA1/ADA2 ratio during the menses, foll...

Ada has been successfully used in many dependable real−time applications, which have undoubtedly benefit of its major strengths: The well defined language semantics [1], the strong type checking, structuring mechanisms like packages and not to forget the Ada Semantic Interface Standard [2] supporting the development of code analysis, verification and testing tools. But an Ada system can not be ...

We read with interest the article by Hikari et al (March 2004)1 comparing the markers of tuberculosis in pleural effusions. We wish to express our disagreement with their statement that interferon (IFN)should be measured routinely in all suspected cases of pleural tuberculosis. They have based their conclusion on the basis of a perfect area under the curve of 1.000 on receiver operator characte...

A specification/generation software tool for building hard real-time distributed systems was redeveloped to generate Ada 95 rather that Ada 83 and targeted to the GNAT Ada 95 compiler under Sun Solaris. The resulting simulator was tested with missile flight simulation code. Language issues discovered and paradigms used are discussed with recommendations in the paper. Performance data is