Dominance has been suggested as one of the genetic mechanisms explaining heterosis. However, using traditional quantitative genetic methods it is difficult to obtain accurate estimates of dominance effects. With the availability of dense SNP (Single Nucleotide Polymorphism) panels, we now have new opportunities for the detection and use of dominance at individual loci. Thus, the aim of this stu...

combining ability, gene action, heritability and other genetic parameters in bread wheat under drought stress condition were evaluated using half diallel design. nine wheat cultivars and 36 derived f1 assessed in a randomized complete block design with three replications in shahid bahonar university of kerman research field in 2013. evaluated genotypes showed high diversity for all traits. gene...

drought stress is one of the most important environmental stresses that affect yield of bread wheat strongly. considering that the yield achieved with the interaction of a large number of plant traits and environment, so the morphological and agronomical traits, can serve as selection criteria under environmental conditions. by genetic analysis and estimation of inheritance and mode of gene act...

Height has been used for more than a century as a model by which to understand quantitative genetic variation in humans. We report that the entire genome appears to contribute to its additive genetic variance. We used genotypes and phenotypes of 11,214 sibling pairs from three countries to partition additive genetic variance across the genome. Using genome scans to estimate the proportion of th...

A hallmark of positive-feedback regulation is bistability, which gives rise to distinct cellular states with high and low expression levels, and that stochasticity in gene expression can cause random transitions between two states, yielding bimodal population distribution (Kaern et al., 2005, Nat Rev Genet 6: 451-464). In this paper, the probability transition rate and first-passage time in an ...

Broccoli and cabbage are important vegetable crops that produce hybrid seeds after insect pollination; the size of floral organs is crucial for this process. To investigate the genetic characteristics of floral organ sizes (corolla width, petal length and width, and lengths of stamen, anther, style, and stigma) and to improve the flower size and breeding efficiency of broccoli, we used multi-ge...

Pentazocine and pethidine have been compared in the dose ratio 45:75 for their depression of respiration in normal subjects. The respective additive actions of the two drugs were investigated by comparing the effects of a single dose with those of two repeated half-doses. Some degree of ventilatory depression was found consistently. A first half-dose of pentazocine 22.5 mg had a greater effect ...

Specifying the reward function of a Markov decision process (MDP) can be demanding, requiring human assessment of the precise quality of, and tradeoffs among, various states and actions. However, reward functions often possess considerable structure which can be leveraged to streamline their specification. We develop new, decisiontheoretically sound heuristics for eliciting rewards for factored...