A 23 year old female with a 12 year history of Crohn's disease had received a variety of systemic and biologic therapies, all of which were either of poor efficacy or had been poorly tolerated. Most recently an end ileostomy and rectal stump had been formed, with a view to ileal pouch formation at a later date. However, our patient continued to develop deep ulceration of the anal verge and dist...