This article proposes a framework for theory and research on risk-taking that is informed by developmental neuroscience. Two fundamental questions motivate this review. First, why does risk-taking increase between childhood and adolescence? Second, why does risk-taking decline between adolescence and adulthood? Risk-taking increases between childhood and adolescence as a result of changes aroun...

A recent offender rehabilitation theory, the ‘Good Lives Model’ (GLM), states that effective interventions should not only focus on risk factors, but also improving well-being by meeting a universal set of human needs, such as relatedness with friends and family, inner peace excellence in agency, called ‘primary goods’. Little empirical research however exists examining GLM's underlying etiolog...

This longitudinal study examined change in adolescents' daily range of emotional states between early and late adolescence. A sample of 220 youth provided reports on their daily emotions at random times during two 1-week periods. At Time 1 they were in the fifth through eighth grades; 4 years later, at Time 2, they were in the ninth through twelfth grades. Results showed that average emotional ...

Highly conserved neural circuitry between rodents and humans has allowed for in-depth characterization of behavioral and molecular processes associated with emotional learning and memory. Despite increased prevalence of affective disorders in adolescent humans, few studies have characterized how associative-emotional learning changes during the transition through adolescence or identified mecha...

The members of electronic communities are often unrelated to each other, they may have never met and have no information on each other's reputation. This kind of information is vital in Electronic Commerce interactions, where the potential counterpart's reputation can be a significant factor in the negotiation strategy. I will investigate two complementary reputation mechanisms that rely on col...

Evidence suggests that children with selective mutism (SM) display significant aberrations in auditory efferent activity at the brainstem level that may underlie inefficient auditory processing during vocalization, and lead to speech avoidance. The objective of the present study was to explore auditory filtering processes at the cortical level in children with SM. The classic paired-click parad...

OBJECTIVES To define clinically relevant reference ("normal") values for cerebrospinal fluid (CSF) protein concentrations in pediatric patients who were evaluated for meningitis by traditional criteria and by enterovirus-polymerase chain reaction (EV-PCR). DESIGN AND PATIENTS A cohort of 906 consecutive pediatric patients to receive CSF analysis at St Louis Children's Hospital, St Louis, Mo, ...

Postnatal cerebral development is a complicated biological process precisely controlled by multiple genes. To understand the molecular mechanism of cerebral development, we compared dynamics of mouse cerebrum transcriptome through three developmental stages using high-throughput RNA-seq technique. Three libraries were generated from the mouse cerebrum at infancy, adolescence and adulthood, resp...

The development of personality across the human life course may be observed from three different standpoints: the person as actor (behaving), agent (striving), and author (narrating). Evident even in infancy, broad differences in social action patterns foreshadow the long-term developmental elaboration of early temperament into adult dispositional traits. Research on personal strivings and othe...

In humans, novelty-seeking behavior peaks in adolescence and is higher in males than females. Relatively, little information is available regarding age and sex differences in response to novelty in rodents. In this study, male and female Lister-hooded rats were tested at early adolescence (postnatal day, pnd, 28), mid-adolescence (pnd 40), or early adulthood (pnd 80) in a novel object recogniti...