نتایج جستجو برای: adrb2

تعداد نتایج: 286  

2011
Gerdien E. de Kloe Chris de Graaf Saskia Nijmeijer Henry F. Vischer Mark H. P. Verheij Anitha Shanmugham Ken Y. Chow Rogier A. Smits Iwan J. P. de Esch

In this study we present the first comprehensive fragment-based chemogenomics analysis of eight protein targets belonging to four diverse target classes, GPCRs, LGICs, phosphodiesterases and kinases. Biochemical fragment screening with a chemically diverse library of 1010 fragment-like molecules, of which the construction and analyses is described, yielded diverse sets of fragment hits for all ...

Journal: :The Journal of endocrinology 2001
T Engstrøm H Vilhardt P Bratholm N J Christensen

The effects of in vivo treatment with estrogen and progesterone on isoproterenol-induced uterine relaxation and beta(2)-adrenoceptor (beta(2)AR) mRNA production in non-pregnant rat myometrium were investigated. Whether homologous myometrial desensitization of beta(2)AR function was dependent on or modulated by the two steroids was also examined. Estrogen treatment alone or in combination with p...

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