One of the early theories in regard to the function of the adrenal gland was that it acted as a detoxifying agent (1, a). While no convindng proof of this hypothesis was presented, many scattered facts have been brought out which show that the adrenals are involved in the reaction of the organism to infection and intoxication, and which suggest that these glands play an important r61e in the pr...

I N 1891 Jacobi described nerves branching from the splanchnics ‘and supplying the adrenal gIands .I Six years later Biedl found that these nerves conveyed vaso-dilator impulses to the glands, and suggested that they probably conveyed also secretory impulses.2 Evidence for this suggestion was presented the following year by Dreyer, who demonstrated that electrical stimulation of the splanchnics...

Congenital adrenal hyperplasia (CAH), also termed adrenogenital syndrome in older literature, is a common inherited form of adrenal insufficiency. This group of diseases is due to mutations (genetic defects) in the genes coding for several enzymes needed for the production of adrenal cortex hormones. About 95% of cases of CAH are caused by 21-hydroxylase deficiency. This enzyme is necessary for...

I N 1891 Jacobi described nerves branching from the splanchnics ‘and supplying the adrenal gIands .I Six years later Biedl found that these nerves conveyed vaso-dilator impulses to the glands, and suggested that they probably conveyed also secretory impulses.2 Evidence for this suggestion was presented the following year by Dreyer, who demonstrated that electrical stimulation of the splanchnics...

I N 1891 Jacobi described nerves branching from the splanchnics ‘and supplying the adrenal gIands .I Six years later Biedl found that these nerves conveyed vaso-dilator impulses to the glands, and suggested that they probably conveyed also secretory impulses.2 Evidence for this suggestion was presented the following year by Dreyer, who demonstrated that electrical stimulation of the splanchnics...

UNLABELLED Composite pheochromocytoma/paraganglioma is a rare tumor with elements of pheochromocytoma/paraganglioma and neurogenic tumor. Most were located in the adrenal glands, and extra-adrenal composite pheochromocytoma is extremely rare. Only 4 cases in the retroperitoneum have been described in the online database PUBMED. Here, we report a case of retroperitoneal extra-adrenal composite p...

Spontaneous adrenal hemorrhage (SAH) is seen in the absence of trauma or adrenal tumor in adrenal glands. The incidence of SAH has been reported from 0.14% to 1.1% and it usually involves the right gland. During pregnancy, idiopathic unilateral SAH has been reported rarely. We present a case which comes to emergency department with an acute abdominal pain and the test results showed spontaneous...

BACKGROUND The differential diagnosis of adrenal pathology depends on the child's age and imaging findings. CASE REPORT Three children without clinical symptoms of neoplasm, with an adrenal lesion discovered on diagnostic ultrasound imaging. Laboratory tests for neoplasm were negative. The final diagnosis was based on histopathological examinations after surgical resection. CONCLUSIONS 1. T...

The turnover of norepinephrine and the enzymes responsible for the synthesis of catecholamines were studied in various organs of rats made hypertensive by DOCA and NaCl. After inhibition of tyrosine hydroxylase by a-methyl-ptyrosine, an increase in the rate of disappearance of endogenous norepinephrine in the heart, intestine, and spleen of hypertensive rats indicated an increased norepinephrin...

To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with reverse-phase high-performance liquid chromato...