Leptin serum concentration in early life is an important factor for adequate future development of the offspring. Previously, we demonstrated that hyperleptinemia on lactation programmed for hyperleptinemia, central leptin resistance with lower expression of the long form of leptin receptor at hypothalamus, and higher medullary catecholamine levels with cardiovascular consequences at adulthood....

The pattern of urinary catecholamine excretion in fasting differs in pregnant and nonpregnant rats, which suggests that the sympathoadrenal response to fasting is altered by pregnancy. In fasting nonpregnant animals, urinary norepinephrine (NE) excretion decreases and epinephrine (E) excretion remains unchanged, whereas the excretion of both catecholamines rises significantly with refeeding. In...

Background: Chemerin is an adipokine typically known for its role in inflammation. Recent studies suggest that it plays a part in the development of obesity and hypertension. Because of the importance of the sympathetic nervous system in blood pressure control and because the adrenal is an important effector of this system, we hypothesized that chemerin would be present in the adrenal glands an...

We report a rare case of solitary paraganglioma arising from the small bowel mesentery, found in 70-year-old female who presented with abdominal pain. Paragangliomas are neuroendocrine, neural crest-derived tumors, most commonly adrenal medulla. While extra-adrenal paragangliomas arise diverse locations, mesenteric origins extremely rare. Our comprehensive review shows 35 previously documented ...

Adrenal yetmezlik olguları, hayatı tehdit eden şok ile karakterize adrenal kriz tablosu karşımıza çıkabileceği gibi özgün olmayan belirtilerle de başvurabilir. Hastaların, mortalite ve morbiditesi yüksek olan öncesinde tanınıp tedavi edilmesi hayati öneme sahiptir. Bu makale Hashimoto tiroditi nedeniyle izlemde iken aşırı kilo kaybı, halsizlik, cilt renginde koyulaşma bulguları gelişen Addison ...