Background: Advanced maternal age, over 35 years, is a well-known risk factor for poor pregnancy outcomes. It commonly associated with various complications, such as spontaneous miscarriage, preeclampsia/ toxemia, gestational diabetes mellitus, preterm labor, stillbirth, chromosomal abnormalities, and cesarean delivery. Objectives: This study assessed obstetric neonatal complications advanced a...

Abstract Background Non-invasive prenatal screening (NIPS) is widely used as the alternative choice for pregnant women at high-risk of fetal aneuploidy. However, whether NIPS has a good detective efficiency advanced maternal age (AMA) not been fully studied especially in Chinese women. Methods Twenty-nine thousand three hundred forty-three AMA with singleton pregnancy who received and followed-...