Mitochondria are the main sites of biological energy generation in eukaryotes. These organelles are remnants of a bacterial endosymbiont that took up residence inside a host cell over 1,500 million years ago. Comparative genomics studies suggest that the mitochondrion is monophyletic in origin. Thus, the original mitochondrial endosymbiont has evolved independently in anaerobic and aerobic envi...

there are many reasons for decrease of the functional activity of the brain like aging of the neurons, bacterial diseases and neuro inflammations. nowadays, the effects of exercise on physical and mental health have been proven but its effects on motor functions as well as neuro inflammation is an issue that has recently been studding. neuro inflammation is a mechanism that can be caused by bac...

aim of present research was to review the probability changes in ghrelin and obestatin hormones following eight weeks aerobic training with moderate intensity in sprague–dawley male rats. for this purpose randomly selected 47 two month age rats from animal lab. all rats made fat by stimulate the appetite with lettuce and vegetables and reached from mean weight 240±15 to 320±20 kg and after that...

Current theory indicates that mitochondria were obtained 1.5 billion years ago from an ancient prokaryote. The mitochondria provided the capacity for aerobic respiration, the creation of the eukaryotic cell, and eventually complex multicellular organisms. Recent reports have found that mitochondria play essential roles in aging and determining lifespan. A variety of heritable and acquired disea...

There is an ongoing debate regarding the efficacy of glycaemic control in critically ill patients. Here we briefly highlight the key function of elevated glucose in critically ill patients, namely, to enable elevation of aerobic glycolysis in rapidly dividing cells. In particular, aerobic glycolysis provides metabolic intermediates necessary for expansion of biomass in immune cells and promotio...

A continuous culture system was developed to examine the cell surface carbohydrates of Bradyrhizobium sp. strain 32H1. When cultures were shifted from aerobic to microaerobic growth conditions, nitrogenase activity was induced and extracellular polysaccharide levels were greatly reduced; however, the levels of cell-associated cyclic beta-1,6 -1,3 glucans were found to be essentially unchanged.

One of the most common abnormalities of cancer cells is their predilection to engage in a high rate of glycolysis despite the continued availability of oxygen. First described by Otto Warburg, this phenomenon of aerobic glycolysis (or the Warburg effect) has recently been proposed to result from cancer-associated alterations in signal transduction pathways. In this issue of The EMBO Journal, Pa...

Aerobic (5-day-old cultures) and nonreplicating (dormant) Mycobacterium tuberculosis (5-, 12-, and 19-day-old cultures) bacteria were treated with rifampin (R), moxifloxacin (MX), metronidazole (MZ), amikacin (AK), or capreomycin (CP) for 7, 14, and 21 days. R-MX-MZ-AK and R-MX-MZ-CP killed both aerobic and dormant bacilli in 21 days, as shown by lack of regrowth in solid and liquid media. R-MX...

Efficient nutrient removal from mixed black water is under challenge in the context of global pollution control and circular economy. The anaerobic-anorexic-aerobic process a widely used biological technology for wastewater treatment, yet its denitrification capacity limited by low biodegradable organics to nitrogen (C/N) ratio due prior degradation water. We have previously proved that weak el...