introduction: aflatoxin b1 (afb1) is one of the most well-known hepatocarcinogens in humans. contamination of raw materials, used in the production of sausages and burgers, with aflatoxin producing molds can lead to increased level of aflatoxin in the final products and can impose hazards to human health. unfortunately, aflatoxin is resistant to heating and freezing processes, etc. and can rema...

Thirty-three samples of wheat of the 1982 crop year from Kansas and Nebraska were analyzed for deoxynivalenol, T-2 toxin, zearalenone, and aflatoxin. Deoxynivalenol was identified in 31 of 33 samples, zearalenone was identified in 3 of 33 samples, and aflatoxin B1 was identified in 23 of 31 samples. One 1982 wheat sample from Illinois and one from Texas were also contaminated with deoxynivaleno...

BACKGROUND Aflatoxins are the most common mycotoxins that contaminate crops. They are produced by fungi such as Aspergillus flavus and Aspergillus parasiticus. Wheat (Tricitumaestivum) is one of the most important staple foods used in Iran, and the environmental conditions in the north of Iran are favorable to fungal growth. This study was designed in order to determine the aflatoxin concentrat...

I. Three experiments using sixty individually fed, enzootic pneumonia-free Large White pigs on experiment from 9-1 I weeks of age to zoo lb live weight are described. 2. Information was obtained on the effect of different dietary concentrations of aflatoxin B1 on the performance of the pigs, on various biochemical measurements and on the histology of the livers and kidneys. 3. Reduced growth ra...

Wild-type Aspergillus parasiticus produces, in addition to the colorless aflatoxins, a number of pigmented secondary metabolites. Examination of these pigments demonstrated that a major component was an anthraquinone, averufanin. Radiolabeling studies with [14C]averufanin showed that 23% of the label was incorporated into aflatoxin B1 by the wild type and that 31% of the label was incorporated ...

-Aflatoxin BI was given by ip injection to year-old female guinea-pigs and 6 hr later aflatoxin B1 and its metabolites were recovered and isolated chromatographically. Approximately 14~ of the administered toxin was represented by the isolated compounds. Aflatoxin B1 and M1 each accounted for approximately 3 7o, and the remaining 94~ was a product that migrated with the solvent front in a chlor...

Aflatoxins are a group of naturally-occurring carcinogens that are known to contaminate different human and animal foodstuffs. Aflatoxin B1 (AFB1) is the most genotoxic hepatocarcinogenic compound of all of the aflatoxins. In this report, we explore the capacity of β-D-glucan (Glu) to reduce the DNA damage induced by AFB1 in mouse hepatocytes. For this purpose, we applied the comet assay to gro...

Aflatoxin B1 (AFB1) is a potent carcinogen that causes growth stunting, immunosuppression and liver cancer in multiple species. The recent trend of replacing fishmeal with plant-based proteins in fish feed has amplified the AFB1 exposure risk in farm-raised fish. NovaSil (NS), a calcium montmorillonite clay, has previously been shown to reduce AFB1 bioavailability safely and efficaciously in se...

conclusions phoma glomerata pg41 strain sharing natural substrate with toxigenic a. flavus secretes metabolites possessing a significant aflatoxin-degrading activity. the activity is associated mainly with a protein-enriched high-molecular-weight fraction of extracellular metabolites and appears to be of enzymatic origin. results the afb1-degrading activity of protein-enriched fractions, isolat...

background: aflatoxin contamination of food and feed stuff is a serious health problem and significant economic concerns. in the present study, the inhibitory effect of candida parapsilosis ip1698 on mycelial growth and aflatoxin production in aflatoxigenic strains of aspergillus species was investigated. methods: mycelial growth inhibitions of nine strains of aflatoxigenic and non-aflatoxigeni...