BACKGROUND Systemic lupus erythematosus (SLE) is a devastating systemic disease that can lead to end-stage renal disease (ESRD). Our goal was to assess the relative mortality risk associated with race in pediatric and adult populations with ESRD secondary to SLE maintained on hemodialysis (HD). METHODS We identified an inception cohort of patients who were started on HD in January 1990 from d...

Researchers currently know very little about how African Americans regard themselves and their salient outgroup (i.e., European Americans). The current study examines how experiences with individual ingroup and outgroup members affect these evaluations on two key dimensions in intergroup research: warmth and competence. In particular, the study asks what effect I-sharing (i.e., sharing a subjec...

The spectrum of mutations in BRCA1 and BRCA2 among African Americans has not been well characterized because most studies to date have been done in Caucasian families. According to Myriad Genetic Laboratories, Inc., only f3% of individuals undergoing BRCA1 /BRCA2 testing reported African American ancestry. Data from previous studies show that among African American women a greater proportion of...

and Invited Presentation: Dec 2013 American Association for Cancer Research (AACR)The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, Atlanta, GA.“Vitamin D and prostate Cancer in African-American Men” Abstract and Poster presentation: November 2015 Steroid Research Congress Chicago. “Vitamin D metabolites in prostate tissue and serum from African...

We used whole-exome and targeted sequencing to characterize somatic mutations in 103 colorectal cancers (CRC) from African Americans, identifying 20 new genes as significantly mutated in CRC. Resequencing 129 Caucasian derived CRCs confirmed a 15-gene set as a preferential target for mutations in African American CRCs. Two predominant genes, ephrin type A receptor 6 (EPHA6) and folliculin (FLCN...

OBJECTIVE The objective of this work was to determine the prevalence, sociodemographic characteristics, and service utilization patterns of African American grandparents raising grandchildren compared with noncaregiving peers. METHODS Data were obtained from the Census 2000 Supplementary Survey/American Community Survey, a nationally representative survey of 890,000 households. Analysis was b...

OBJECTIVES Little is known about polytobacco use among African-American adults. This study is the first to explore this among a random, statewide, community sample of African-American adults. SETTING Community-based sampling obtained a random, household-probability sample of African-American adults from California, surveyed door to door in randomly selected census tracts statewide. PARTICIP...

PURPOSE To examine how family history of cancer influences the mammography screening behaviors of asymptomatic African-American women. METHODS Using the National Health Interview Survey's 2000 Cancer Control Module, the authors performed bivariate analyses and multivariate logistic regressions with SAS/SUDAAN due to the complex sampling design. RESULTS Of the 1,531 African-American women in...

BACKGROUND HIV/sexually transmitted infections (STIs) and drug abuse remain significant public health concerns in the United States, and African American and Hispanic youth are disproportionately affected. Although technology-based interventions are efficacious in preventing and reducing HIV/STI and licit/illicit drug use behaviors, relatively little is known regarding the state of the science ...

Since publication of the U.S. Surgeon General's report Mental Health: Culture, Race and Ethnicity--A Supplement to Mental Health: A Report of the Surgeon General (U.S. Department of Health and Human Services, 2001), several federal initiatives signal a sustained focus on addressing African American-White American disparities in mental health treatment access and quality and open the way to unpr...