BACKGROUND Standard morphological features of endomyocardial biopsy specimens do not necessarily correlate with the efficacy of immunotherapy or development of cardiac allograft vasculopathy (CAV). We hypothesized that expression of allograft inflammatory factor-1 (AIF-1), a cytokine-inducible, calcium-binding protein associated with vascular smooth muscle cell proliferation, would be associate...

Allograft inflammatory factor-1 (AIF-1) is a cytoplasmic, calcium-binding, inflammation-responsive scaffold protein. Several studies have reported increased AIF-1 expression in activated macrophages and have implicated AIF-1 as a marker of activated macrophages. However, the function of AIF-1 in macrophages and the mechanism whereby it participates in macrophage activation are unknown at this t...

In the difficult economic conditions in Russia, caused, as all countries, by consequences of coronavirus pandemic, search for additional government revenues is becoming especially relevant. All possibilities cutting budget expenditures are being considered, including optimization number civil servants. The deputies State Duma Russia over past month have been actively discussing effectiveness fu...

unsustainability and precarious conditions of agricultural production have caused this sector be associated with risk . crops insurance is efficient tool for controlling and reducing production and market risk and stabilizing farmers' income. in this study, the thinking system approach by using of i think software is used for analyzing and modeling of the effects of different alternatives of po...

This paper presents preliminary findings from a research project that examines the interaction between informal risk sharing, index insurance and risk-taking. We have randomized rainfall insurance contracts offered to cultivating and landless households in a set of Indian villages where pre-existing census data on caste networks allows us to characterize the nature and extent of informal risk s...

Free heme is potentially cytotoxic, particularly in the presence of oxidants or activated phagocytes. Daintain/AIF-1 (allograft inflammatory factor-1) is a macrophage factor that has been implicated in the regulation of inflammation. In the present study, daintain/AIF-1 was found to induce cytolysis of erythrocytes, resulting in heme release in vitro. Furthermore, the interacting protein of dai...