AHF (acute heart failure) causes significant morbidity and mortality. Recent studies have postulated that the expression of inflammatory mediators, such as cytokines and chemokines, plays an important role in the development and progression of heart failure. A pro-inflammatory state has been postulated as a key factor in triggering CMV (cytomegalovirus) reactivation. Therefore we sought to dete...

AIM Acute heart failure (AHF) critically deranges haemodynamic and metabolic homoeostasis. Iron is a key micronutrient for homoeostasis maintenance. We hypothesized that iron deficiency (ID) defined as depleted iron stores accompanied by unmet cellular iron requirements would in this setting predict the poor outcome. METHODS AND RESULTS Among 165 AHF patients (age 65 ± 12 years, 81% men, 31% ...

BACKGROUND Acute heart failure (AHF) is a serious condition that is associated with increased mortality in critically ill patients. Previous studies indicated that environmental exposure to cadmium increases mortality of general populations. However, the relationship of cadmium exposure and mortality is unclear for AHF patients. MATERIALS AND METHODS A total of 153 patients with AHF in intens...

Objective To identify the clinical and laboratory predictors of short-term mortality in patients with acute heart failure (AHF). Subjects and methods We conducted a prospective, single center study on 120 consecutive patients presented with acute heart failure to the emergency department. All patients had clinical, laboratory, electrocardiographic and echocardiographic evaluation. Short-term ...

The aim of this study was to evaluate the ability of Neutrophil Gelatinase-Associated Lipocalin (NGAL) to predict clinically relevant worsening renal function (WRF) in acute heart failure (AHF). Plasma NGAL and serum creatinine changes during the first 4 days of admission were investigated in 1447 patients hospitalized for AHF and enrolled in the Placebo-Controlled Randomized Study of the Selec...

BackgroundInflammation and malnutrition are common problems in patients who hospitalized for acute heart failure (AHF). C-reactive protein (CRP) is an acute-phase reactant nonspecific marker evaluating systemic inflammation. There has been growing interest prealbumin nutritional assessment. Additionally, a negative because its synthesis suppressed the inflammatory setting which cytokines stimul...

Many patients with acute heart failure have marked hypertension and preserved left ventricular ejection fraction. In these patients, the heart failure usually does not result from transient systolic dysfunction or valvular abnormalities but rather results from diastolic dysfunction. Treatment of this condition includes control of hypertension, cautious diuresis, and, if necessary, ventilatory s...

Abstract Objective This study aims to evaluate the difference between dobutamine and milrinone in patients presenting with acute decompensated heart failure (AHF). Background Inotropes are indicated for treating AHF, especially concomitant hypoperfusion indicative of cardiogenic shock. However, previous studies have not identified optimal inotrope. We sought compare outcomes associated versus A...

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main source(s): This work was supported by a grant from the Institute Medical Sciences, University Opole, Poland. Background Acute heart failure (AHF) is life-threatening multifaceted clinical condition requiring intensive and expensive treatment. Earlier studies highlighted difference in characteristics prognosis...