نتایج جستجو برای: alad

تعداد نتایج: 242  

2006
D. P. Gaillot C. J. Summers

An advanced dielectric function has been designed to compute the photonic band structures of non-close-packed inverse opals fabricated using conformal infiltration and by a recently described sacrificial-layer technique. A model is proposed to correctly simulate complex dielectric structures resulting from conformal backfilled infiltrations. While large photonic band gaps PBGs and a reduced ref...

Journal: :Biochemistry 2001
J Kervinen E K Jaffe F Stauffer R Neier A Wlodawer A Zdanov

4,7-Dioxosebacic acid (4,7-DOSA) is an active site-directed irreversible inhibitor of porphobilinogen synthase (PBGS). PBGS catalyzes the first common step in the biosynthesis of the tetrapyrrole cofactors such as heme, vitamin B(12), and chlorophyll. 4,7-DOSA was designed as an analogue of a proposed reaction intermediate in the physiological PBGS-catalyzed condensation of two molecules of 5-a...

Journal: :Antimicrobial agents and chemotherapy 2010
Ilka U Heinemann Claudia Schulz Wolf-Dieter Schubert Dirk W Heinz Yang-G Wang Yuichi Kobayashi Yuuki Awa Masaaki Wachi Dieter Jahn Martina Jahn

The recently discovered antibacterial compound alaremycin, produced by Streptomyces sp. A012304, structurally closely resembles 5-aminolevulinic acid, the substrate of porphobilinogen synthase. During the initial steps of heme biosynthesis, two molecules of 5-aminolevulinic acid are asymmetrically condensed to porphobilinogen. Alaremycin was found to efficiently inhibit the growth of both Gram-...

2016
F. Oliveira J. Christiansen B. Dandurand A. Eberhard

In this paper, we propose a novel decomposition approach for mixed-integer stochastic programming (SMIP) problems that is inspired by the combination of penalty-based Lagrangian and block Gauss-Seidel methods (PBGS). In this sense, PBGS is developed such that the inherent decomposable structure that SMIPs present can be exploited in a computationally efficient manner. The performance of the pro...

1998
Kurt Busch Sajeev John

We present a detailed study of photonic band structure in certain self-organizing systems that self-assemble into large-scale photonic crystals with photonic band gaps ~PBGs! or pseudogaps in the near-visible frequency regime. These include colloidal suspensions, inverted opals, and macroporous silicon. We show that complete three-dimensional PBGs spanning roughly 10% and 15% of the gap center ...

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