Acute lung injury (ALI) is an inflammatory lung disease that manifests itself in patients as acute respiratory distress syndrome and thereby contributes significantly to the morbidity and mortality of patients experiencing critical illness. Even though it may seem counterintuitive, as the lungs are typically well-oxygenated organs, hypoxia signaling pathways have recently been implicated in the...

Cysteine-rich protein-61 (CYR61), also known as connective tissue growth factor, CYR61, and nephroblastoma overexpressed gene 1 (CCN1), is a heparin-binding protein member of the CCN family of matricellular proteins. Gene expression profiles showed that Cyr61 is upregulated in human acute lung injury (ALI), but its functional role is unclear. We hypothesized that CYR61 contributes to ALI in mic...

Submitted for the MAR05 Meeting of The American Physical Society Superfluidity of interacting bosons in one-dimension via strong disorder NOAH BRAY-ALI, UC Berkeley, Physics Department, JOEL MOORE, UC Berkeley, Physics Department; Lawrence Berkeley National Laboratory, Materials Science Division — We have found a novel set of superfluid and Mott insulating phases arising in strongly-disordered,...

This study aims to analyze online word-of-mouth regarding notebook computers, based on two large notebook computer forums in Taiwan. Online reviews are extracted between January 1, 2008 and April 1, 2010, with a total of 318 effective samples collected. Empirical study found that the market of the notebook computer can be divided into four groups, namely, game and entertainment, fashion and qua...

KEMAL ALI GER 1, PATRICIA ARNESON 1, CHARLES REMINGTON GOLDMAN 1 AND SWEE JOO TEH 2* 1 DEPARTMENT OF ENVIRONMENTAL SCIENCE AND POLICY, UNIVERSITY OF CALIFORNIA, DAVIS, CA 95616, USA AND AQUATIC TOXICOLOGY PROGRAM, DEPARTMENT OF ANATOMY, PHYSIOLOGY, AND CELL BIOLOGY, SCHOOL OF VETERINARY MEDICINE, DEPARTMENT OF ANATOMY, PHYSIOLOGY AND CELL BIOLOGY, UNIVERSITY OF CALIFORNIA, 1321 HARING HALL, ONE...

OBJECTIVES We observed early acute lung injury (ALI) after a switch from veno-arterial extracorporeal life support (VA-ECLS) to long-term mechanical circulatory support (MCS). The aim of our study was to analyse the frequency, impact on mortality and characteristics of patients presenting ALI after MCS implantation in the bridge-to-bridge (BTB) strategy. METHODS We retrospectively analysed da...

RATIONALE Acute lung injury (ALI) that develops 6 hours after transfusion (TRALI) is the leading cause of transfusion-related mortality. Several transfusion characteristics have been postulated as risk factors for TRALI, but the evidence is limited to retrospective studies. OBJECTIVES To compare patient and transfusion risk factors between patients who do and do not develop ALI. METHODS In ...

Essentials Tissue factor (TF) represents a central link between hemostasis and inflammation. We studied the roles of myeloid and airway epithelial TF in acid-caused acute lung injury (ALI). TF on myeloid cells displays a non-coagulatory role regulating the inflammatory response in ALI. Airway epithelial TF contributes to hemostatic functions, but is dispensable in ALI pathogenesis. SUMMARY In...

CONTEXT Acute lung injury (ALI) and ARDS are currently defined by the American-European Consensus Conference (AECC) definition criteria, which contain a radiographic criterion. The accuracy or reliability of this consensus radiographic definition has not been evaluated, and no radiographic definition of ALI-ARDS has been evaluated by a large international group of experts. OBJECTIVE To study ...

The National Aeronautics and Space Administration (NASA) Landsat program has been dedicated to sustaining data continuity over the 20-year period during which Landsat Thematic Mapper (TM) and Enhanced TM Plus (ETM+) sensors have been acquiring images of the earth's surface. In 2000, NASA launched the Earth Observing-1 (EO-1) Advanced Land Imager (ALI) to test new technology that could improve t...