In tropical legumes like Glycine, Phaseolus and Vigna sp., ammonia as direct product of symbiotic nitrogen fixation is converted to ureides (allantoin and allantoic acid) and they were translocated to the shoots as nitrogen source. In the xylem sap of soybean in reproductive phase the ureides reached to 60-75% of soluble nitrogen. In nodules infected cells (plastid and mitochondria) and uninfec...

The intracellular location of enzymes involved in the synthesis of the ureides, allantoin and allantoic acid, was investigated in nodules of Glycine max L. Merr. Cellular organelles were separated on isopycnic sucrose density gradients. Xanthine dehydrogenase activity (270 nanomoles per min per gram fresh weight) was totally soluble, whereas approximately 15% of the total uricase and catalase a...

and in mice bearing Ehrlich ascites tumor has been investigated. The results indicate that the exogenous compound is utilized equally well for the synthesis of both adenine and guanine of deoxyribonucleic acid and ribonucleic acid. No evidence for the incor poration of intact 6-methylaminopurine into the nucleic acids of liver, kidney, spleen, intestine, or tumor cells was obtained. The princip...

Eight young rhesus monkeys were fed a purified diet devoid of vitamin E. After from 6 to 13 months of feeding, all the animals developed signs of vitamin E deficiency. The signs of vitamin E deficiency in the monkey include muscular dystrophy, elevated excretion of creatine, allantoin, and free amino acids and decreased excretion of creatinine. The vitamin E-deficient monkeys all developed anem...

bioactive products from snail slime of “helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. however, the poor pharmacokinetics characteristics of these natural compounds limit their use. nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug delivery sys...

Since the early work on uricase carried out by Schittenhelm (l), Wiechowski (a), and Battelli and Stern (3), and t,he elucidation of the structure of uric acid by the work of Behrend and Roosen (4), Fischer (5), and Biltz (6), the chemical nature of the intermediates and end-products of uricase action has been uncertain. The first indications of the structure of a possible intermediate were off...