BACKGROUND Fluticasone propionate is a new inhaled corticosteroid with a 2:1 efficacy ratio compared with beclomethasone dipropionate with regard to lung function and symptom scores, without increased systemic activity. The aim of this study was to investigate whether this was also the case for bronchial hyperresponsiveness, assessed by both a direct (histamine) and an indirect (ultrasonically ...

The aim of the study was to evaluate the possible use of atopy patch test in the diagnosis of atopic dermatitis and to characterize an optimal standardized system for atopy patch test in terms of allergen concentrations and time of allergen exposure. The study included 36 patients with atopic dermatitis and IgE-mediated airborne allergy. Patients presented positive results of skin prick tests a...

PURPOSE TOP CAST Paediatric Allergen Mix test is a new cellular in vitro test based on evaluation of leukotrienes synthesised by basophils under the influence of specific allergens. The aim of the study was evaluation of applicability of this test as screening examination in diagnosis of atopic asthma in children. MATERIAL AND METHODS The study was carried out on a group of 30 children (56.7%...

BackgroundProvocation tests are widely used in allergology to objectively reveal patients’ sensitivity specific allergens. The objective quantification of an allergic reaction is a crucial characteristic these tests. Because the absence quantitative measurements, conjunctival provocation test (CPT) less frequently method despite its and simplicity.ObjectiveWe developed new artificial intelligen...

Four cases are reported of occupational asthma due to amylase derived from Bacillus licheniformis, used in detergent washing powders. It is thought that these are the first reported cases of asthma due to this enzyme in the detergent industry. All four employees (men) were from the same factory and none had a history of asthma or atopy. All developed symptoms of wheeze at work after an initial ...

OBJECTIVE To update the scientific evidence of subcutaneous immunotherapy (SCIT) in children. DATA SOURCES PubMed, EMBASE, and known articles. STUDY SELECTION All publications on SCIT in pediatric patients from January 2006 to April 2011. Study design was not a restriction. The articles were analyzed according to their outcomes and evaluated on their scientific quality using the Grading of ...

We wanted to determine whether changes in bronchial hyperresponsiveness (BHR) following allergen challenge show a time relationship with inflammatory events in the airways of allergic asthmatic subjects. Lavage was performed and endobronchial biopsies were taken via the fiberoptic bronchoscope, before, and 3 and 24 h after, allergen challenge, on separate occasions, in nine dual asthmatic respo...

BACKGROUND Allergic rhinitis and asthma may be associated, bronchial hyperreactivity (BHR) is quite common in AR patients. It has been reported that allergen bronchial challenge induces nasal inflammation. Methacholine (MCH) is a stimulus able to elicit BHR. There is no study that investigated the effect of MCH bronchial challenge on the nose. OBJECTIVE The aim of this study was to evaluate w...

Rupture of the bronchus has become more common in the last decade, mainly due to an increase in road traffic accidents. In spite of this increase it is still relatively rare, and most thoracic surgeons do not have the personal experience of treating more than two or three cases in their life-time. In 1947 Kinsella and Johnsrud reviewed the world literature on intrathoracic rupture of the trache...

BACKGROUND A very weak relationship has been reported between the health-related quality of life (HRQL) of patients with asthma and their degree of airway hyper-responsiveness (AHR), evaluated in terms of sensitivity. However, this relationship still has not been sufficiently explored for bronchial reactivity indices. OBJECTIVES To analyse the relationship between bronchial reactivity and sen...