Purpose: Diltiazem, a calcium ion cellular influx inhibitor is known for its limited and variable bioavailability. This study is intended to explore the benefits of microemulsion formulation as oral drug delivery system for immediate release to improve the bioavailability and efficacy of Diltiazem. Methods: Oil in water microemulsion was prepared using the simple water titration method. The opt...

Beta-caryophyllene (BCP) and docosahexaenoic acid (DHA) are components of several plants with documented anti-inflammatory and analgesic effects in animal pain models. In the present study, in vitro and in vivo tests were carried out to evaluate their effects, alone or in combination, during long-lasting administration in a model of persistent pain. IR spectra of the two compounds were obtained...

Characterizations of fatty acids composition in % of total methylester of fatty acids (FAMEs) of fourteen vegetable oils--safflower, grape, silybum marianum, hemp, sunflower, wheat germ, pumpkin seed, sesame, rice bran, almond, rapeseed, peanut, olive, and coconut oil--were obtained by using gas chromatography (GC). Saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA),...

Nemaguard has been the workhorse rootstock of the California almond industry for many decades. It is well adapted to the well-drained, non-calcareous loam and sandy loam soils common throughout the San Joaquin Valley. Nemaguard is vigorous, immune to rootknot nematode, compatible with all almond varieties, doesn’t sucker much, has decent anchorage and is easy to grow at the nursery. However, th...

conductance in almond and olive in response to water stress 2 3 RUNNING TITLE: LEAF HYDRAULIC FUNCTION IN ALMOND AND OLIVE 4 5 VIRGINIA HERNANDEZ-SANTANA*, CELIA M. RODRIGUEZ-DOMINGUEZ, J. 6 ENRIQUE FERNÁNDEZ, ANTONIO DIAZ-ESPEJO 7 Irrigation and Crop Ecophysiology Group, Instituto de Recursos Naturales y 8 Agrobiología de Sevilla (IRNAS, CSIC). Avenida Reina Mercedes, no 10, 410129 Sevilla, Sp...

Buffer type, pH and ionic strength, as well as the fraction of polyvinylpyrrolidone were optimized for efficient extraction of b-galactosidase from almond seeds. The enzyme was purified up to electrophoretic homogeneity employing (NH4)2SO4 (15–60 %) fractionation, size exclusion and ion-exchange chromatography. Molecular mass of b-galactosidase as estimated by gel filtration and SDS-PAGE was ap...

Almond seeds age rapidly during storage at high relative humidity (80%) an d moderate temperature (20°C). The content of lipid decreased during accelerated ageing up to 40 d. The levels of linoleic (Cl8:2) and linolenic (Cl8:3) acids in almond lipid fraction also decreased during agei/lg up to 20 d. The aged seeds contain high levels of malondialdehyde, a product of the peroxidatio/l of unsatur...

UNLABELLED Whole Nonpareil variety almonds were inoculated with Salmonella Enteritidis PT 30 and stored at 4 or 23 °C for up to 48 wk. At 1, 12, 24, 37, and 48 wk of storage, almonds were heated by immersion in 121 °C oil. After heating for 0.5 to 2.5 min, almonds were drained, transferred to tryptic soy broth, and mixed with a stomacher prior to plating onto tryptic soy and bismuth sulfite aga...