Introduction: Early diagnosis of Hepatocellular Carcinoma (HCC) by imaging and biochemical tests would be valuable in controlling morbidity mortality associated with this most common primary hepatic malignancy which is the third leading cause global cancer-related deaths. Objective: To determine an association between level serum Alpha Fetoprotein (AFP) size tumor (HCC).Materials & Methods:...

Deviations from the normal of alpha-fetoprotein (AFP) concentrations in fetal serum, amniotic fluid, maternal serum and adult human serum can be explained by understanding the normal physiology and the pathophysiology of AFP synthesis and metabolism. AFP is the prototype of oncofetal markers. Emphasis is given to the usefulness of elevated serum AFP levels on the diagnosis and management of pri...

Alpha-fetoprotein (AFP) is the main component of mammalian fetal serum. It is synthesized by visceral endoderm of the yolk sac and by fetal liver. Immediately after birth AFP level in blood decreases dramatically. AFP synthesis is reactivated in liver tumors and germinogeneous teratoblastomas, in a lesser degree after chemical and mechanical liver injuries followed by regeneration (i.e., acute ...

The gene encoding alpha fetoprotein (locus symbol Afp) was assigned to rat chromosome 14 at band p21-p22 using fluorescence in situ hybridization method. The present result suggests that there is a conserved syntenic group between human 4q11-q13, mouse 5F-G, and rat 14p21-p22.

the gene encoding alpha fetoprotein (locus symbol afp) was assigned to rat chromosome 14 at band p21-p22 using fluorescence in situ hybridization method. the present result suggests that there is a conserved syntenic group between human 4q11-q13, mouse 5f-g, and rat 14p21-p22.