BACKGROUND Differentiation among types of muscular dystrophy (MD) has remained challenging. In this retrospective study, we sought to develop a methodology for differentiation of MD types using analysis of serum enzyme profiles. METHODS The serum levels of enzymes from 232 patients, including 120 with DMD, 36 with BMD, 36 with FSHD, 46 with LGMD, and 11 with EDMD, were evaluated. RESULTS Th...

There is a very little information about the protective effect of lycopene (LYC) against hepatic ischemia-reperfusion injury. The present study was designed to examine the possible protective effect of the strong antioxidant and anti-inflammatory agent, LYC, on hepatic ischemia/reperfusion injury. For this purpose, rats were subjected to 45 min of hepatic ischemia followed by 60 min of reperfus...

the aim of the present study was to determine the protective action of silymarin on acute toxicity due totetracycline severe overdose in cats. thirty healthy cats were randomly allotted into five equal groups. catsin group a were given tetracycline (single dose 120 mg⁄kg, p.o.); group b consisted of cats that receivedsilymarin (single dose 30 mg⁄kg, p.o.) concurrent with tetracycline administra...

BACKGROUND Our study aimed to demonstrate the frequency of the syndrome of inappropriate ADH secretion (SIADH) and associated factors during the course of brucellosis in children and adolescents. MATERIAL AND METHODS The study included children and adolescents aged 0-18 years old diagnosed with brucellosis between 2012 and 2014. The data were collected from patient charts. The diagnosis of bruc...

PURPOSE To investigate the relationship between lactate dehydrogenase A (LDH-A) expression, lactate concentration, cell metabolism, and metastases in murine 4T1 breast tumors. EXPERIMENTAL DESIGN Inhibition of LDH-A expression and protein levels were achieved in a metastatic breast cancer cell line (4T1) using short hairpin RNA (shRNA) technology. The relationship between tumor LDH-A protein ...

PURPOSE D-dimer, LDH and tumor markers are usually overexpressed in colorectal carcinomas (CRC). Our purpose was to assess the prognostic role of D-dimer, lactate dehydrogenase (LDH), CEA, CA19-9 and CA72-4 in patients with metastatic CRC treated with XELOX chemotherapy. METHODS Thirty-eight CRC patients who had evidence of distant metastasis were enrolled in the study and blood samples were ...

OBJECTIVE Although the association between alanine aminotransferase (ALT) levels and risk of type 2 diabetes is well-studied, the effects of slightly increased ALT levels within the normal range on the temporal normal glucose profile remains poorly understood. METHODS A total of 322 Chinese subjects without impaired glucose tolerance or previous diagnoses of diabetes were recruited for study ...

this study was conducted to determine the effect of dietary turmeric rhizome powder (trp) as a natural antioxidant, and soybean oil, canola oil and tallow on lipid metabolism, blood metabolites, immune system, and antioxidant status of broiler chickens before (bhs, 28 d) and after exposure to heat stress (ahs, 42 d). seven hundred and ninety two d-old male arian broilers were randomly allotted ...

PPOK menjadi permasalahan kesehatan yang semakin mengkhawatirkan pada masyarakat di seluruh dunia. Usaha deteksi dini terus dikembangkan untuk mencegah perkembangan penyakit. Penggunaan parameter pemeriksaan laboratorium rutin dan sederhana dinilai berpotensi sebagai penanda PPOK. Pengujian aktivitas enzim terhadap spesimen darah adalah biasa diterapkan diagnosis berbagai penyakit akut kronik. ...