John Ioannidis argues that problem base, context placement, information gain, pragmatism, patient centeredness, value for money, feasibility, and transparency define useful clinical research. He suggests most clinical research is not useful and reform is overdue.

Genetic-specific nondiscrimination laws have been enacted in most states, but the laws are ineffective and increase the stigma of genetic conditions. Whether these laws are better than no new legislation depends on their consequences and a recognition of their limitations.

Modern institutional economists look to pragmatism for: (1) an evolutionary philosophy of knowledge; and (2) a foundation of a theory of human nature. These two elements are combined in William James, who was both a philosopher of pragmatism and a pioneering experimental psychologist. The author shows first how William James added psychological depth to the pragmatic tradition as it was left by...

Some of the best brains in North America have worked for over a year to produce the Institute of Medicine's (IOM) report on vitamin D (1) and so we expect expertise and wise words. However, despite great care in sifting evidence, careful application of method and a desire for transparency, the report has turned out to be very controversial. Its wisdom and method are now being questioned, as can...

Despite fiscal stress, public confidence in the National Health Service (NHS) remains strong; privatisation has not hollowed out the service. But if long term challenges are to be overcome, pragmatism not rhetoric should be the guide.

This paper explores the intertwinement of ontology and history that happened after idealist turn Kantian transcendentalism, particularly in classic German idealism later American pragmatism. The focuses on less remarked-upon consequence this intertwinement, namely possibility a new reading based changes concepts habitual mentality. proposes take historiography vindicates Hegel’s insight but his...

BACKGROUND Subsistence norms are part of the "ecosophy" or ecological philosophy of Alaska Native Peoples in the sub-Arctic, such as the Inupiat of Seward Peninsula. This kind of animistic pragmatism is a special source of practical wisdom that spans over thousands of years and which has been instrumental in the Iñupiat's struggle to survive and thrive in harsh and evolving environments. OBJE...

in this article, in order to demonstrate the pragmatic elements of rawls’s viewpoint, the developmental path of his a theory of justice shall first be investigated. this development has two phases: in the first phase, justice has an ethical-philosophical basis. in a theory of justice, this phase is specifically shown under the title of theory of justice. in the second phase, justice has no phil...