BACKGROUND Anti-Mullerian hormone (AMH) is constantly secreted during menstrual cycles and may offer several advantages over traditional biomarkers of ovarian reserve. OBJECTIVE To assess the relationship of anti-Mullerian hormone (AMH) values, which are used to evaluate ovary reserves, with oocyte and embryo quality and with ART outcomes in patients undergoing intra-cytoplasmic sperm injecti...

Serum concentration of anti-mullerian hormone (AMH) is used as a biomarker in practical clinics. As bone morphogenetic protein (BMP) cytokines induce AMH expression in human granulosa cells (GC) in vitro, serum concentrations of BMP cytokines and AMH were evaluated whether there would be a relationship between BMP cytokines and AMH. Serum concentrations of BMP-2, -6 -7, AMH and FSH were measure...

BACKGROUND The manual Generation II (Gen II) ELISA method used to measure Anti-Müllerian Hormone (AMH) from Beckman Coulter has recently been superseded by a fully automated AMH immunoassay. The aim of this study was to evaluate the performance of the Access AMH assay and directly compare it to the modified Gen II ELISA method. A secondary aim was to verify that the fertile age-related AMH rang...

Printed by Summary It is believed that endometriosis has significant damaging effect on ovarian reserve. With regards to the effect of endometrioma on AMH levels, currently available evidence provides conflicting views; ranging significantly lower AMH measurements in smaller studies, to no association between AMH and endometrioma in more robust studies (Uncu et. al. 2013, Hwu et. al. 2013, Stre...

BACKGROUND Testicular tumours are common in dogs and in many cases do not give rise to clinical signs. In other cases, signs of feminization, hyperpigmentation or alopecia may be observed, most commonly associated with Sertoli cell tumours (SCT). Although these signs are often associated with elevated concentrations of oestradiol, analysis of oestradiol may give inconclusive results due to larg...

BACKGROUND In mammals, the ovarian follicular reserve is highly variable between individuals and impacts strongly on ovarian function and fertility. Nowadays, the best endocrine marker of this reserve in human, mouse and cattle is the anti-Müllerian hormone (AMH). The objectives of this work were to determine whether AMH could be detected in the plasma of prepubertal ewe lambs and to assess its...

BACKGROUND No data regarding metformin effects on follicular fluid anti-Müllerian hormone (AMH) levels were to date available in literature. The aim of the present study was to evaluate in patients with polycystic ovary syndrome (PCOS) whether metformin administration affects serum and follicular AMH levels, and whether this is related to ovarian response to the treatment. METHODS Twenty youn...

Background Polycystic ovary syndrome (PCOS) is the major cause of anovulatory infertility in women. The level of serum Anti-Mullerian Hormone (AMH) in patients can be 2-3 times higher than in healthy women. The aim of this study was to assess the effect of metformin on AMH level in PCOS patients suffering from infertility. Methods In this pre and post clinical trial, 30 infertile patients wit...

In Sertoli cells, anti-Müllerian hormone (AMH) expression is upregulated by FSH via cyclic AMP (cAMP), although no classical cAMP response elements exist in the AMH promoter. The response to cAMP involves NF-κB and AP2; however, targeted mutagenesis of their binding sites in the AMH promoter do not completely abolish the response. In this work we assessed whether SOX9, SF1, GATA4, and AP1 might...

In the ovary, Anti-Mulllerian hormone (AMH) is produced by the granulosa cells of early developing follicles. The aim of our study was to assess the value of the AMH as a test to predict ovarian damage in groups of infertile women. Ninety seven infertile women were divided into four groups: (G1=29) with regular menstrual cycle, (G2=30) with prolonged or irregular cycles, (G3=21) with secondary ...