BACKGROUND Methamphetamine is a major drug of abuse with no effective pharmacotherapy available. Trace amine associated receptor 1 is implicated in cocaine addiction and represents a potential therapeutic target. However, the effects of trace amine associated receptor 1 agonists on addiction-related behavioral effects of methamphetamine are unknown. METHODS This study examined the effects of ...

Soda lignin was divided into two fractions with different molecular weights by methanol extraction. Lignin amine was synthesized from the low-molecular-weight lignin fraction via Mannich reaction and was used for interfacial modification of poly-(vinylchloride) (PVC)/wood-flour composites. The PVC/wood-flour composites were prepared from surface-treated wood flour and PVC by melt compounding. T...

Polymers have gained an extensive application due to their versatility of properties and benefits. Hence, the polymer blends composites reinforced with different infusions at scales, macro nanofillers, can be fabricated, leading specific tailormade applications. The main objective this investigation is overview various studies carried out reuse waste materials like electroplating sludge, fly as...

A stimuli-responsive hexameric oligophenol host undergoes amine-induced co-operative folding from a more fluorescent, more linear structure into less fluorescent, more curved or helically folded states, enabling easy identification and classification of the bound amine guests.

Multi-responsive amphiphilic gold nanoparticles (AuNPs) protected by graft poly(ether amine) have been prepared simply by a one-pot photochemical synthesis in the presence of thio-graft poly(ether amine) (gPEA-SH) and the mechanism was studied in detail.

Mechanical point-chirality in a [2]rotaxane is utilized for asymmetric catalysis. Stable enantiomers of the rotaxane result from a bulky group in the middle of the thread preventing a benzylic amide macrocycle shuttling between different sides of a prochiral center, creating point chirality in the vicinity of a secondary amine group. The resulting mechanochirogenesis delivers enantioselective o...

The semicarbazide-sensitive amine oxidases constitute a group of copper-containing enzymes whose physiological function is unclear. The enzymes are present in various tissues, including blood plasma. At present, the source of the plasma enzyme in humans is not known. Results of a recent study suggested that semicarbazide-sensitive amine oxidase is expressed in the skeleton, e.g. in the spine. U...

The aim of this study was to measure the postprandial changes in amino acid and biogenic amine profiles in individuals with impaired fasting glucose (IFG) and to investigate the changes of postprandial amino acid and biogenic amine profiles after a meal of highland barley (HB). Firstly, 50 IFG and 50 healthy individuals were recruited for the measurement of 2 h postprandial changes of amino aci...

The localization of labeled amine in the heart of the bat after administration of tritiated norepinephrine (NE) was studied by means of electron microscope autoradiography. Monoamine oxidase was inhibited so that the distribution of amine in both neuronal (Uptake(1)) and extraneuronal (Uptake(2)) sites could be analyzed. Labeling was nonrandom in both the atrial and ventricular myocardium. The ...