conclusions the results of this study indicated that the genes encoding aminoglycoside-modifying enzymes are prevalent in a. baumannii isolates in the study region, which highlighted the necessity of considering preventive measures to control dissemination of these resistance genes. results antimicrobial susceptibility analysis showed that the highest resistance was towards beta−lactam antibiot...

The inhibitory effect of neutrophil chemotaxis of gentamicin, tobramycin, and sisomicin was shown. The combined effect of aminoglycosides and histamine was not additive.

Purpose Data on aminoglycoside stewardship in critically ill septic patients with acute kidney injury (AKI) needing intermittent hemodialysis (IH) are scarce. The first objective of the study was to evaluate whether administration occurs before vs after IH real-life management AKI IH. second assess delay achieving a potential reinjection window for dose aminoglycoside, which should be obtained ...