CASE 1 A 19-year-old Bantu man was admitted to Miguel Bombarda Hospital on 3 December 1963. Mild, vague, upper abdominal pain had commenced one month earlier and was associated with chills and fever, generalized malaise, weakness and weight loss. Two weeks later a slight bulge appeared in the right upper quadrant. His symptoms increased in severity and jaundice appeared; there was no nausea or ...

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Liver amoebic abscess was produced by introducing 16,000 trophozoites of Entamoeba histolytica directly into the livers of growing hamsters. A group of the infected animals received orally 64 mg metronidazole/kg body weight for 5 days from the day of the infection. The treated group was autopsied 7 or 14 days after the treatment. Histologically, liquefaction of large parenchymal areas and bioch...