The essential oil (EO) from leaves of Annona neosalicifolia H. Rainer (Annonaceae) obtained two chemotypes in the southern Brazilian Atlantic Rainforest was analysed both by GC-FID and GC-MS. Forty compounds were identified, accounting for 95.9 to 99.5% total each sample. VOs characterized predominance sesquiterpenes all samples, being main bicyclogermacrene (13.9-41.8%) beta-caryophyllene (9.3...

Six nitrogen-, sulfur- and cyclopropane-containing derivatives of cholestanol were examined as inhibitors of growth and sterol biosynthesis in the trypanosomatid protozoan Crithidia fasciculata. The concentrations of inhibitors in the culture medium required for 50% inhibition of growth were 0.32 microM for 24-thia-5 alpha,20 xi-cholestan-3 beta-ol (2), 0.009 microM for 24-methyl-24-aza-5 alpha...

Background: The canonical Wnt signal transduction (or the Wnt/β-catenin pathway) plays a crucial role in the development of animals and in carcinogenesis. Beta-catenin is the central component of this signaling pathway. The activation of Wnt/β-catenin signaling results in the cytoplasmic and nuclear accumulation of β-catenin. In the nucleus, β-catenin interacts with the TCF/LEF transcription fa...

martindale proved that under some conditions every multiplicative isomorphism between two rings is additive. in this paper, we extend this theorem to a larger class of mappings and conclude that every multiplicative $(alpha, beta)-$derivation is additive.

Patients with antiphospholipid syndrome are characterized by the association of thrombosis or pregnancy morbidity and the presence of antiphospholipid autoantibodies. Particularly, anti-beta(2)-glycoprotein (beta(2) GPI) autoantibodies correlate with thrombosis, suggesting an antibody-induced gain of prothrombotic function and/or an antibody-induced loss of antithrombotic function of beta(2) GP...

This note considers the application of electronic cash to transactions in which many small amounts must be paid to the same payee and in which it is not possible to just pay the total amount afterwards. The most notable example of such a transaction is payment for phone calls. If currently published electronic cash systems are used and a full payment protocol is executed for each of the small a...