BACKGROUND The kidneys ability to concentrate and dilute urine is deteriorated during progressive renal insufficiency. We wanted to test the hypothesis that these phenomena could be attributed to an abnormal function of the principal cells in the distal part of the nephron. METHODS Healthy control subjects and patients with chronic kidney diseases were studied. Group 1 comprised healthy subje...

BACKGROUND Neisseria meningitidis, a life-threatening human pathogen with the potential to cause large epidemics, can be isolated from the nasopharynx of 5-15% of adults. The aim of the current study was to evaluate biophysical and biochemical properties and immunological aspects of chimeric acyl-carrier protein-macrophage infectivity potentiator protein-type IV pilus biogenesis protein antigen...

PURPOSE Amp C beta-lactamase are Ambler class C enzymes that confer resistance to extended spectrum cephalosporins and are not inhibited by beta-lactamase inhibitors. Their detection is crucial, since the phenotypic tests are not standardised leading to ambiguity in interpretation of results. This study was done to detect the types of Amp C prevalent in Escherichia coli and Klebsiella pneumonia...

Abstract. The isotopic composition of nitrogen and oxygen in dioxide (NO2) potentially carries a wealth information about the dynamics oxides (NOx = nitric oxide (NO) + NO2) chemistry atmosphere. While isotopes NO2 are subtle indicators NOx emissions chemistry, believed to reflect only O3 / VOC chemical regime different atmospheric environments. In order access this potential tracer tropospheri...

The presence of endogenous phosphorylase kinase and phosphorylase phosphatase in crude extracts of fat bodies from the cockroaches Nauphoeta cinerea and Periplaneta americana is demonstrated in vitro by activation/inactivation of glycogen phosphorylase under appropriate conditions. Fractionation of fat body extracts of both cockroach species on an anion-exchange medium results in the elution of...

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A significant decline of serum 25-hydroxyvitamin D concentration [25(OH)D] with increasing latitude has been reported only for Caucasians. To determine the association between serum 25(OH)D and geographic location and its impact on bone mineral density (BMD) in an Asian population, a total of 17,508 subjects (8910 men and 8598 women) from the 2008-2010 Korea National Health and Nutrition Examin...

The advancements and reliance on digital data necessitates dependence information technology. growing amount of their availability over the Internet have given rise to problem security. With increase in connectivity among devices networks, maintaining security an asset has now become essential for organization. Intrusion detection systems (IDS) are widely used networks protection against differ...

o a a A chieving circuit-level insight into the fundamental nature of psychiatric symptoms has long proven elusive. Technological limitations have traditionally prevented cell type-tareted and temporally precise interventions into intact mammalian eural circuitry to elicit or ameliorate expression of disease sympom-related phenotypes. However, recent years have seen a growng wave of application...

Rickettsia prowazekii possesses an exchange transport system for AMP. Chromatographic analysis of the rickettsiae demonstrated that transported AMP appeared intracellularly as AMP, ADP, and ATP, and no hydrolytic products appeared in either the intracellular or extracellular compartments. The phosphorylation of AMP to ADP and ATP was prevented by pretreatment of the cells with 1 mM N-ethylmalei...