background: limiting dilution assay is considered as the gold standard method for quantifying the number of parasites in the animal model of leishmania infection. nowadays, real-time pcr is being increasingly applied to quantify infectious agents. in the present study , a real-time pcr assay was developed to estimate para­site burdens in lymph nodes of leishmania major infected balb/c mice. enu...

objective(s) seed of cucumis sativus linn. is one of the herbal remedies has been traditionally used for diabetes mellitus treatment. we studied the effect of hydroalcoholic and buthanolic extract obtained from c. sativus seeds in a model of streptozotocin (stz)-induced diabetic (type i) rats. materials and methods normal and diabetic male wistar rats (stz, 60 mg/kg, intraperitoneal) were treat...

abstract unbalance using of chemical fertilizers cause decline the soil quality and fertility, environmental pollution and specially soil and water resources pollution. the use of animal manure is a replacement to chemical fertilizers. therefore, recognizing of demographic, technical-extensional and agronomic affect on farmer's decision making process to use of animal manure will have important...

objective: the aim of this study was to determine the protective effects of coriandrum sativum on acetic acid-inducedcolitis in rats. c. sativum (coriander) has long been used in iranian traditional medicine and its use as an anti-inflammatory agent is still common in some herbal formulations.  materials and methods: colitis was induced by intra-rectal administration of 2ml acetic acid 4% in fa...

the main aim of this research was to estimate the genetic and phenotypic parameters for productive and reproductive traits of esfahan native chickens. traits included body weights at hatch (bw1), 8 weeks of age (bw8), 12 weeks of age (bw12), and at sexual maturity (wsm)], age at sex maturity (asm), egg number (en), average egg weight (aew) in the first 12 weeks of production, and egg production...

there are only a few, non-evidence based, neuroprotective strategies for treatment and prevention of brain injuries after closed head trauma. to establish new therapy strategies, a novel animal model is needed. the aim of our investigation was to link standardized small animal models and actual patient medical care. data of experimental small animal studies often cannot be transferred to cns in...

Phenylketonuria (PKU) is a genetic disorder in which the hydroxylation of phenylalanine (Phe) to tyrosine is severely disrupted. If PKU is left untreated, severe mental retardation results. The accepted treatment is to restrict dietary intake of Phe. It has generally been thought that cognitive impairments are prevented if levels of Phe in plasma are maintained at or below five times the normal...

An animal model of cicatrizing trachoma was developed in cynomolgus monkeys. This model is consistent with our hypothesis that repeated ocular inoculation of Chlamydia trachomatis, BOUR strain, mimics the repeated reinfection that occurs naturally in endemic human trachoma. A chronic follicular conjunctivitis developed, and scarring later appeared in the superior tarsal conjunctiva. The organis...

The dramatically increasing prevalence of obesity, associated with potentially life-threatening health problems, including cardiovascular diseases and type II diabetes, poses an enormous public health problem. It has been proposed that the obesity epidemic can be explained by the concept of 'food addiction'. In this review we focus on possible similarities between binge eating disorder (BED), w...