نتایج جستجو برای: ana negative lupus
تعداد نتایج: 583916 فیلتر نتایج به سال:
OBJECTIVES ACPA is a highly specific marker for RA. It was recently reported that ACPA can be used to classify RA into two disease subsets, ACPA-positive and ACPA-negative RA. ACPA-positive RA was found to be associated with the HLA-DR shared epitope (SE), but ACPA negative was not. However, the suspicion remained that this result was caused by the ACPA-negative RA subset containing patients wi...
Subacute cutaneous lupus erythematosus (SCLE) is a variant of photosensitive cutaneous lupus erythematosus that is often associated with anti-Ro antibodies. We present 3 cases of treatment-refractory SCLE that resolved satisfactorily with rituximab. Patient 1 was a 54-year-old woman (smoker) diagnosed with SCLE. She had annular lesions on her back (Fig. 1 A), upper chest, and arms. Testing for ...
Valvular heart disease is the most important cardiac manifestation of systemic lupus erythematosus (SLE). However, severe mitral valve regurgitation necessitating valvular surgery due to SLE is rare. We report a 22-year-old male patient presenting with symptoms of congestive heart failure initially in whom lupus and severe mitral valve regurgitation were diagnosed. In our patient, four of the A...
INTRODUCTION Neonatal lupus erythematosus (NLE) presents clinically with either cutaneous lesions or cardiac involvement and is related to the transplacental passage of anti-Ro antibodies from mother to foetus. We report a series of 10 cases seen at the National Skin Centre between 1990 and 1998 including a pair of siblings. CLINICAL PICTURE The female to male ratio was 2.3:1 and most present...
BACKGROUND Neonatal Lupus Erythematosus (NLE) is an uncommon autoimmune disease characterized by cutaneous, hepatic, hematological, neurological and cardiac involvement. CASE PRESENTATION Here we report four cases of cutaneous NLE which were referred to our department in the last 10 years and update literature. The newborns presented with different skin, clinical and laboratory features. This...
Sir, Subacute cutaneous lupus erythematosus (SCLE), first described by Sontheimer et al. (1) in 1979, represents a distinct subtype of lupus erythematosus (LE) with specific clinical and serological features. Characteristically, skin lesions appear in a non-scarring papulosquamous, annular, polycyclic or psoriasiform pattern primarily located in the sun-exposed areas such as the upper back and ...
BACKGROUND Antinuclear antibodies (ANA) are a hallmark of many autoimmune diseases and can be detected many years before disease onset. Autoimmune thyroid diseases (AITD) are frequently associated with other organ- and non-organ-specific autoimmune disorders. Objectives. To assess the prevalence of ANA in pediatric patients with AITD and their clinical correlations. METHODS Ninety-three conse...
Background: Recently developed EULAR/ACR classification criteria for systemic lupus erythematosus (SLE) have important differences compared to the 2012 Systemic Lupus International Collaborating Clinics (SLICC) SLE and revised 1997 American College of Rheumatology (ACR) criteria: The obligatory entry criterion antinuclear antibody (ANA) positivity is introduced a “weighted” approach used 1 . Se...
Methods: Case report A 16 year-old girl presented with a painful left breast mass associated with localized skin erythema. Her medical history was significant for diffuse proliferative lupus nephritis that was diagnosed in 2002. After 2 years of immunosuppression therapy, the patient had stable renal function for more than 8 years. In January 2013, she presented with a painful nodule in the lef...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید