Isolated human skin mast cells (HSMC) were prepared and cultured overnight before functional and electron microscopic studies. Mast cell suspensions were examined after stimulation with anti-IgE to produce anaphylactic degranulation or examined in buffer-incubated controls. Histamine release was measured in replicate samples. Control, isolated HSMC studied by electron microscopy were well prese...

BACKGROUND A type-IV-allergic reaction to German camomile (Matricaria chamomilla) in a form of allergic contact dermatitis is not unusual. However, only a few cases of anaphylactic reaction to camomile have been described in the literature. CASE SUMMARY We present the case of a 38-year-old Caucasian man who developed an episode of severe anaphylaxis with generalized urticaria, angioedema and ...

Corresponding author: Krzysztof Pałgan MD Department of Allergology, Clinical Immunology and Internal Diseases Nicolaus Copernicus University Collegium Medicum 75 Ujejskiego St 85-168 Bydgoszcz, Poland Phone: +48 52 365 54 16 Fax: +48 52 348 40 76 E-mail: [email protected] Department of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum of L. Rydygier in Bydgoszcz, Nicolaus C...

Diclofenac is a non-steroidal anti-inflammatory agent used in degenerative joint disease, rheumatoid arthritis, and allied conditions.' Its commonest unwanted effects include gastrointestinal disorders, rashes, peripheral oedema, and abnormalities of serum transaminase activity. More rarely, melaena and haematemesis, myoclonic encephalopathy, and myoclonus of the lower limbs may occur.2 3 We re...

The anaphylaxis is an allergic reaction. An allergic reaction is a spontaneous and exaggerate reaction of the body to a particular substance. These substances, called allergens, cause production of antibodies when enter the body. The exposition with the substance happens by inhalation, ingestion, contact or inoculation of the allergen. Every substance can act as allergen. Among the more frequen...

1. The serum ferments are practically unaltered by a primary injection of foreign protein. 2. During the course of sensitization the injection of the antigen is followed by the mobilization of a non-specific protease which increases in rapidity and intensity as the maximum period of sensitization is reached. 3. Acute shock is accompanied by: (a) The instantaneous mobilization of a large amount ...

We describe a case of anaphylactic reaction in a 46-year-old female post application of decongestant nose drops containing benzalkonium chloride (BAC). With some latency, the patient complained of cough, dyspnea, sensation of heat, croakiness and pruritus. Since she showed all of these symptoms, typical of an anaphylactic reaction, we proceeded some weeks later with a prick test with solutions ...

Although systemic hyperfibrino(geno)lysis during hypotensive crisis is known, there do not seem to be recent reports of episodes of primary acute fibrinogenolysis during anaphylactic shock. We report the case of a 61-year-old male admitted to the hospital for anaphylactic shock due to an insect bite who presented a clinical and laboratory picture of severe acute generalized hyperfibrinogenolysi...