abstract it is becoming evident that oral hormonal contraceptives –besides being well established contraceptives – seem to become important medications for many functional or organic disturbances. so far, clinical effectiveness has been shown for treatment as well as prevention of menstrual bleeding disorders and menstrual-related pain symptoms. also this is true for premenstrual syndrome (pms)...

Due to the content of phytosterols, extractive preparations Urtica dioica roots are able show antiandrogenic effect in case external therapy men and women with androgenic alopecia. Oil extracts (OE) characterized by several advantages when applied skin scalp compared water-alcohol extracts. For development OE technology from roots, it is important choose optimal extraction parameters, which bas...

Recurrent episodes of painful papules and nodules, mostly located on the labia minora , have been reported under denominations vulvar sebaceous adenitis (14 published cases) acne (16 cases). The primary aim this study was to delve further into clinical pathological features condition. secondary collect therapeutic data. In retrospective cohort files photographs patients with or nodules inner ma...

Objectives: To understand that adipose stem cell exosome (ASCE) can be a paradigm shift in regenerative aesthetics & therapeutics. know ASCE make scalp rejuvenation and hair loss prevention. Introduction: Exosomes are nano-sized (30 – 200 nm diameter) lipid bilayered vesicles secreted by most types. Adipose Stem Cell-derived emerging as promising cell-free therapy for the treatment of rejuvenat...

we present a 21-years old woman with alopecia universalis, generalized vitiligo, and graves' disease. she had had thyroidectomy in early childhood and was receiving replacement therapy with levothyroxine. the patient was treated with systemic puva and glucocorticoid in combination with topical treatment for alopecia. after 6 months of treatment, alopecia was reversed but vitiligo was unchanged.

BACKGROUND Alopecia can be a manifestation of mycosis fungoides (MF) and Sézary syndrome (SS), but the prevalence is unknown. OBJECTIVE We sought to describe the clinicopathologic presentation and molecular features of alopecia in patients with MF/SS. METHODS A retrospective chart review of a prospectively collected MF/SS database was used to identify patients with alopecia. The National Al...

In the U.S. and worldwide anabolic/androgenic steroid use remains high in the adolescent population. This is concerning given that anabolic/androgenic steroid use is associated with a higher incidence of aggressive behavior during exposure and anxiety during withdrawal. This study uses pubertal Syrian hamsters (Mesocricetus auratus) to investigate the hypothesis that an inverse behavioral relat...

This study shows that the androgen receptor agonistic potency is clearly concealed by the effects of androgen receptor antagonists in a total sediment extract, demonstrating that toxicity screening of total extracts is not enough to evaluate the full in vitro endocrine disrupting potential of a complex chemical mixture, as encountered in the environment. The anti-androgenic compounds were maski...

Diffuse alopecia is mainly caused by telogen effluvium, diffuse androgenetic alopecia (female-pattern hair loss) and diffuse alopecia areata. Differential diagnosis between the three disorders may be difficult in several occasions. In this second part of our study, chronic telogen effluvium and diffuse alopecia areata are discussed in detail, including clinical, dermoscopic and histological asp...