Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential. Silymarin, a flavonol lignan mixture) extracted from the Silybum marianum (milk thistle) is a popular remedy for hepatic diseases. Today every herbal company is marketing formulations for liver disorders but th...

Andrographolide (AND), the diterpene lactone compound, was purified by HPLC from the methanolic fraction of the plant Andrographis paniculata. The compound was found to have potent antiplasmodial activity when tested in isolation and in combination with curcumin and artesunate against the erythrocytic stages of Plasmodium falciparum in vitro and Plasmodium berghei ANKA in vivo. IC(50)s for arte...

Andrographolide and wedelolactone are active components of Andrographis paniculata and Eclipta alba, respectively. The extracts of these plants are used in many traditional hepatoprotective formulations. An attempt has been made to develop an accurate, precise and specific HPTLC method to quantify simultaneously both these chemical markers of diversified chemical structures in different dosage ...

Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus that has recently engendered large epidemics around the world. There is no specific antiviral for treatment of patients infected with CHIKV, and development of compounds with significant anti-CHIKV activity that can be further developed to a practical therapy is urgently required. Andrographolide is derived from Andrographis p...

The phytochemical, antimicrobial activity against gram negative and positive bacteria and fungi, DPPH radical scavenging and FRAP assay antioxidant activities of aqueous and organic crude extracts of Millingtonia hortensis, Andrographis paniculata, Aegle marmelos, Coccinia grandis, Tinospora cordifolia, Achyranthus aspera was studied invitro. The phytochemical screening of crude plant extracts ...

The dichloromethane (DCM) extract of Andrographis paniculata Nees was tested for cardiovascular activity. The extract significantly reduced coronary perfusion pressure by up to 24.5 ± 3.0 mm Hg at a 3 mg dose and also reduced heart rate by up to 49.5 ± 11.4 beats/minute at this dose. Five labdane diterpenes, 14-deoxy-12-hydroxyandrographolide (1), 14-deoxy-11,12-didehydroandrographolide (2), 14...

The moisture content present in human skin makes it look young and the use of moisturizer results in fastening the moisture with a surface film of oil. Acne vulgaris is one of the most commonly seen diseases among the youth. The present study is focused on the use of herbs as moisturizer for acne treatment. The anti-acne moisturizer was formulated from herbal crude extracts and investigated the...

Andrographis paniculata (Burm. f.) Nees is a potential medicinal herb used to treat wide range of diseases. Various geographical origins this might lead the diversity herbal quality. The research aims establish chemical fingerprint for quality control and find out markers discrimination from different origin through chemometrics approach. A high performance liquid chromatography photo diode arr...

Diabetes Mellitus is a chronic health problem with devastating effect that characterized by high blood glucose levels resulting from faults or flaws in insulin production action. The unaffordability and adverse effects of conventional drugs the treatment management many diseases has spurred interest scientists to use herbal medicine treat manage ailments. purpose this study was investigate prop...