Internal carotid-posterior communicating artery (IC-PC) aneurysms account for more than 20% of all intracranial aneurysms. As a result of the increase in coiling, there has also been an increase in recurrent IC-PC aneurysms after coiling. We present our experience of 10 recurrent IC-PC aneurysms after coiling that were retreated using surgical or endovascular techniques in order to discuss the ...

The recent publication of the results of the international study on unruptured intracranial aneurysms highlighted a paradox: there do not seem to be enough unruptured aneurysms in the population to account for the observed incidence of subarachnoid haemorrhage. Some authors have suggested that the answer to this paradox is that most aneurysms that bleed do so shortly after formation. This would...

BACKGROUND AND PURPOSE Endovascular treatment of wide-necked aneurysms remains a therapeutic challenge. We conducted this study to evaluate the angiographic results and clinical outcome of patients treated with stent-assisted coiling by using a recently available self-expandable intracranial stent. METHODS A retrospective review of all patients treated with self-expandable stent-assisted coil...

The incidence of subarachnoid haemorrhage (SAH) is 6-8 per 100 000 person years, peaking in the sixth decade. SAH, mostly due to rupture of an intracranial aneurysm, accounts for a quarter of cerebrovascular deaths. Aneurysms increase in frequency with age beyond the third decade, are 1.6 times more common in women and are associated with a number of genetic conditions. Prospective autopsy and ...

BACKGROUND AND PURPOSE Inflammation may play an important role in the formation and rupture of cerebral aneurysms. Chemokines act as chemoattractants for leukocytes directing them toward sites of tissue inflammation. The purpose of this study was to determine whether chemokines and chemoattractant cytokines were increased in the lumen of human cerebral aneurysms. METHODS The concentrations of...

BACKGROUND Intraprocedural rupture and thrombus formation are serious complications during coiling of ruptured intracranial aneurysms, and they more often occur in patients with anterior communicating artery (ACoA) aneurysms. OBJECTIVE To identify independent predictors of intraprocedural rupture and thrombus formation during coiling of ruptured ACoA aneurysms. METHODS Between January 2008 ...

BACKGROUND The off-label use of flow diverters in the treatment of distal aneurysms continues to be debated. OBJECTIVE To report our multicenter experience in the treatment of complex anterior cerebral artery aneurysms with the Pipeline embolization device (PED). METHODS The neurointerventional databases of the four participating institutions were retrospectively reviewed for aneurysms trea...

Background Both aortic aneurysms and coronary artery ectasia (CAE) frequently coexist and are associated with more pronounced inflammation. Neutrophil to lymphocyte ratio (NL ratio) is widely used as a marker of inflammation. However, relation between CAE and NL ratio in patients with aortic aneurysms is not fully understood. This study was undertaken to assess relation between CAE and NL ratio...

BACKGROUND Early multicenter trials of Guglielmi detachable coil embolization of posterior circulations aneurysms have been followed by the publication of numerous single-center experiences. Summary of Review- We performed a MEDLINE literature search and extracted data from single-center reports containing at least 10 posterior circulation aneurysms. Twelve reports (495 aneurysms) were specific...

Endoluminal occlusion of giant intracranial aneurysms with coil embolization is a viable endovascular treatment option alternative to surgical clipping. However, due to the relatively large aneurysm size, the use of embolization coils for giant aneurysms could be great. A loose-packing embolization strategy in which the fundus of the aneurysm is loosely packed while the aneurysm base is tightly...