نتایج جستجو برای: angiotensinogen m235t polymorphism
تعداد نتایج: 109322 فیلتر نتایج به سال:
Angiotensinogen gene G-6A polymorphism influences idiopathic pulmonary fibrosis disease progression.
Angiotensin II is a growth factor that plays a key role in the physiopathology of idiopathic pulmonary fibrosis (IPF). A nucleotide substitution of an adenine instead of a guanine (G-6A) in the proximal promoter region of angiotensinogen (AGT), the precursor of angiotensin II, has been associated with an increased gene transcription rate. In order to investigate whether the G-6A polymorphism of...
Angiotensinogen (AGT) gene polymorphisms have been linked to increased risk of hypertension, but the data remain controversial. In this study we review the most commonly investigated polymorphisms at the AGT locus (other than M235T) and provide summary estimates regarding their association with essential hypertension, while addressing heterogeneity, as well as publication biases. Data on 26 818...
The aim of the current study was to investigate the association between the InDel polymorphism in the angiotensin I-converting enzyme gene (ACE) and the rs699 polymorphism in the angiotensinogen gene (AGT) and diabetes mellitus type 2 (DM2) in a sample population from Southern Brazil. A case-control study was conducted with 228 patients with DM2 and 183 controls without DM2. The ACE InDel polym...
In 2001, the search for gene polymorphism has become a popular challenge in every cardiovascular journal and congress, particularly concerning hypertension and myocardial infarction. These studies were aimed at detecting markers for drug efficacy and risk factors and more generally at better understanding the determinants of these complex diseases that are both multifactorial and multigenic. Fo...
BACKGROUND AND PURPOSE Our objective was to investigate the associations between polymorphisms in representative genes of the renin angiotensin system with measures of cerebral blood flow regulation in older adults. METHODS Participants in this analysis were white subjects (n=335) in the MOBILIZE Boston study (Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly of B...
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