Materials and methods: In Experiment One, 180 seventeen-day-old YorkshireLandrace pigs were randomly assigned to three dietary treatments, including an unsupplemented, unmedicated basal diet (Control) and the basal diet supplemented with either 55 g per tonne carbadox (Phibro Animal Health, Ridgefield Park, New Jersey) or 1.5 kg per tonne oregano oil (Van Beek Scientific, Orange City, Iowa). In...

Native cartilage matrix derived (CMD) scaffolds from various animal and human sources have drawn attention in cartilage tissue engineering due to the demonstrable presence of bioactive components. Different chemical and physical treatments have been employed to enhance the micro-architecture of CMD scaffolds. In this study we have assessed the typical effects of physical cross-linking methods, ...

Acute kidney injury (AKI) is a major global health problem; much research has been conducted on AKI, and numerous agents have shown benefit in animal studies, but none have translated into treatments. There is, therefore, a pressing unmet need to increase knowledge of the pathophysiology of AKI. Multiphoton microscopy (MPM) provides a tool to non-invasively visualize dynamic events in real time...

The fish production industry has become one of the most important animal projects, and suffer from feed costs, so this study aims to find accessible food additives that increase or reduce costs. This was done by 126 common carp (Cyprinus carpio L.) Average individual weight 42.72 g ± 2.28 g. 254.78 2.95 biomass weight. were randomly distributed 21 aquaria, with seven treatments three replicates...

BACKGROUND MR-guided focused ultrasound or high-intensity focused ultrasound (MRgFUS/MRgHIFU) is a non-invasive therapeutic modality with many potential applications in areas such as cancer therapy, drug delivery, and blood-brain barrier opening. However, the large financial costs involved in developing preclinical MRgFUS systems represent a barrier to research groups interested in developing n...

the objective of the present study was to determine if modifications would occur due to epinephrine perfusion and simulating stressful situations (2 µg/ kg/ min, an animal)and transportation,causing change of the values of extractable protein concentrations, sds page profiles and the calpain calpastatin complex in silver rabbit longissimus muscles resulting in consequent changes in meat tendern...

As influenced by agricultural practices, soil organic matter (SOM) stability is imperative in maintaining fertility and crop production. Integrated management practices have been recommended for improvement enhancing matter. We examined the SOM under integrated six consecutive cropping seasons high potential area of Central Highlands Kenya. The experimental design was a complete randomized bloc...

Viable new treatments for depression and anxiety have been slow to emerge, likely owing to the complex and incompletely understood etiology of these disorders. A budding area of research with great therapeutic promise involves the study of resilience, the adaptive maintenance of normal physiology and behavior despite exposure to marked psychological stress. This phenomenon, documented in both h...

Heterotopic ossification (HO) is the formation of marrow-containing bone outside of the normal skeleton. Acquired HO following traumatic events is a common and costly clinical complication. In contrast, hereditary HO is rarer, progressive, and life-threatening. Substantial effort has been directed towards understanding the mechanisms underlying HO and finding efficient treatments. However, one ...

Animal models are often used to test the effectiveness of a drug or procedure before proceeding to clinical trials. One reason for use of animal models is that they allow researchers to focus on particular pathological processes without the confounding effects of other injuries and treatments. However, it is essential that their results are valid and precise. Biased or imprecise results from an...