We report the case of a 29-year-old female patient who presented with an acute onset of anisocoria, blurred vision, nausea and severe left-sided headache. There was no history of trauma, drug abuse, or instillation of topical mydriatic compounds. The ocular history was negative for similar events. On presentation, her visual acuity was 0.2 in the left and 1.0 in the right eye with a +2.5 dpt sp...

BACKGROUND Triple A syndrome (or Allgrove syndrome) is a rare autosomal recessive disorder characterized by alacrima, achalasia, adrenal insufficiency and autonomic/neurological abnormalities. The majority of cases are caused by mutations in the AAAS gene located on chromosome 12q13. However, the clinical picture as well as genetic testing may be complex since symptomatology is variable and mut...

Intracerebral hemorrhage is one of the most devastating forms of stroke especially in the posterior fossa. Expansion of cerebral hematomas was common in the acute phase (< 6 hours) but rarely reported 24 hours later. A 70-year-old man, with history of hypertension, was admitted to the emergency service with the complaint of headache, dizziness and vomiting. He was neurologically intact except f...

PURPOSE We report 3 cases of unilateral blepharoptosis after orbital medial wall reconstruction and describe the cause and clinical outcome. METHODS Observational case series. RESULTS Three previously healthy patients underwent reconstruction for orbital medial wall fracture. All 3 patients had complete unilateral upper eyelid ptosis with no levator palpebrae superioris muscle function imme...

BACKGROUND In birds there are reports of intracranial lesions but not of the clinical, computed tomographic and histopathologic features of acute intraparenchymal cerebral haemorrhage in Iberian golden eagle. CASE PRESENTATION The following report describes a case of a 30-year-old Iberian golden eagle (Aquila chrysaetos homeyeri) with no history of trauma, presented with acute opisthotonus, l...

An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia with right decerebrate posturing) were present in seven of these nine patient...

Introduction. Leptomeningeal carcinomatosis occurs in about 5% of cancer patients. Ocular involvement is a common clinical manifestation and often the presenting clinical feature. Materials and Methods. We report the case of a 52-year old lady with optic neuritis as isolated manifestation of neoplastic meningitis and a review of ocular involvement in neoplastic meningitis. Ocular symptoms were ...

The patient was a 50-year-old woman who had had frequency of urination and numbness of the left side of the trunk for a few years. Neurologic examination showed slight anisocoria (right > left), asymmetry of muscle stretch reflex (right > left) in both upper and lower extremities, hypalgesia and thermohypesthesia of the left side of the trunk, and hypopallesthesia in the right lower extremity. ...

Neurology Service, State University of Rio de Janeiro (UERJ), Rio de Janeiro RJ, Brazil; Laboratory of Panic & Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro (UFRJ), INCT Translational Medicine, Rio de Janeiro RJ, Brazil. Superficial siderosis (SS) of the central nervous system (CNS) is a rare disorder characterized by a classic triad of symptoms consisting of sensor...

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology which affects most frequently the hilar lymph nodes and lungs. Symptomatic involvement of the central nervous system may develop in patients diagnosed with sarcoidosis or it may be the initial manifestation of the disease. This is a case report of 48-year old female patient admitted to our clinic for evaluation of working ...