Many attempts have been made to treat diabetes mellitus with oral medic ation, but none of them seems to have been successful. It has been known that a decoction of Eunymus alata sieb growing in Japan has a blood sugar lowering ac tion. The effective component was isolated, crystallized, and identified as oxaloacetic acid (OAA) by infrared spectral analysis . Stable salt of O AA (OAA sodium) wa...

BACKGROUND There are no published data regarding fracture risk in type 2 diabetic patients in Korea. In this study, we compared the fracture incidence and risk of osteoporosis of type 2 diabetic female patients with those in a non-diabetic hypertensive cohort. METHODS The incidence of fracture in a type 2 diabetic cohort was compared with that in a non-diabetic hypertensive cohort over the co...

It has been also reported that that H. pylori infection may be responsible for some endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus and primary hyperparathyroidism. H. pylori which express cytotoxin-associated gene A (CagA) may be more virulent than those that do not. The aim was to evaluate the seroprevalence of anti-H. pylori IgG and anti-CagA  antibodies in patien...

BACKGROUND AND OBJECTIVES Intentional weight loss, by reducing insulin resistance, results in both better glycemic control and decreased need for anti-diabetic medications. However, not everyone who is successful with weight loss is able to reduce anti-diabetic medication use. In this retrospective cohort study, we assessed the predictive accuracy of baseline triglyceride (TGL)/HDL ratio, a mar...

AIMS Previously, a retrospective cohort study found no increased risk of acute pancreatitis with current or recent use of exenatide twice daily compared with use of other anti-diabetic drugs. This follow-up study investigated incident acute pancreatitis, with the use of a different data source and analytic method, in patients exposed to exenatide twice daily compared with patients exposed to ot...