OBJECTIVE Simultaneous pancreas-kidney transplantation is an effective treatment for patients with type 1 diabetes mellitus and end-stage chronic kidney disease. Delayed pancreatic graft function is a common and multifactor condition with significant impact in short-term outcome of simultaneous pancreas-kidney transplantations. The aim of this study was to analyze the impact of pancreatic delay...

Clinical pancreatic islet transplantation is under evaluation for the treatment of autoimmune diabetes, yet several limitations preclude widespread use. For example, there is a critical shortage of human pancreas donors. Xenotransplantation may solve this problem, yet it evokes a rigorous immune response which can lead to graft rejection. Alpha-1-antitrypsin (AAT), a clinically available and sa...

it is difficult to reconstruct an alar defect with cartilage involvement. here in the authors report a case of traumatic alar loss during childhood in which an alar reconstruction was carried out with a composite auricular graft put over the pedicle buccal flap which was rotated and passed through the intraoral side. the lining skin and auricular cartilage for the flap was obtained from the aur...

Law enforcement agencies are a separate type of public authorities whose main task is to protect and defend the rights freedoms citizens through implementation preventive, criminal procedural, administrative jurisdictional, operational investigative functions. The list law Ukraine includes: Security Service Ukraine, National Police State Bureau Investigation, Economic Anti-Corruption Bureau; Bo...

INTRODUCTION Chronic Hepatitis C Virus (HCV) infection has been associated with glomerular disease in native and transplanted kidneys. We evaluated the presence of HCV infection at the time of transplantation and occurrence of proteinuria in Egyptian kidney transplant patients and their link with graft survival. MATERIALS AND METHODS This retrospective study was done on 273 patients with end-...

background:  renal transplantation is the best choose in the end stage renal disease (esrd), and acute rejection and graft dysfunction remain major challenges in the worldwide, even with the advent of new immunosuppressive drugs. the novel cell-based anti-rejection treatments have been studied by using different stem cell sources. in this study, transplantation of autologous-bone-marrow-derived...

Nephrectomy of a failed kidney transplant is indicated for hematuria and local pain (usually attributed to rejection), but may be done electively to facilitate cessation of immunosuppression. Transplant nephrectomy may also limit long-term cardiovascular risk (1). Despite these potential benefits, transplant nephrectomy can be complicated by morbidities surrounding surgery, and several retrospe...

Should agencies confine their role to main duty or should they embrace new and desirable societal objectives? This article first discusses two emblematic examples of mission expansion: socially responsible competition authorities green central banks. It then sheds light on the ongoing debate using contributions bureaucratic design in economics political science. On that basis, it warns against ...