Mixed ligand Ni(II) complexes of the type [M(Q)(L) x 2H2O] have been synthesized by using 8-hydroxyquinoline (HQ) as a primary ligand and N- and/or O- donor amino acids (HL) such as L-serine, L-isoleucine, L-proline, 4-hydroxy-L-proline and L-threonine as secondary ligands. The metal complexes have been characterized on the basis of elemental analysis, electrical conductance, room temperature m...

BACKGROUND Acute Infective Conjunctivitis may be due to viral or bacterial infection; though it is usually self limiting, topical antibiotics are often prescribed for rapid recovery. OBJECTIVES This study aims to find out prevalence of bacterial infection among cases of acute infective conjunctivitis and to determine their in-vitro antibacterial susceptibilities to commonly used antibacterial...

Article history: Received: 2 August 2011 Revised: 12 September 2011 Accepted: 19 October 2011 Available online: 2 November 2011 Background: Wound infections are associated with increased morbidity and mortality. Etiologic agents of wound infections vary with geographical locations. This study was conducted to assess the prevalence of wound infections, the effect of age and gender on the prevale...

Background Over the decades, new antibacterial agents have been developed in an attempt to combat drug resistance, but they remain unsuccessful. Recently, a novel class of bacterial gene expression regulators, bacterial small RNAs (sRNAs), has received increasing attention toward their involvement in antibiotic resistance. This systematic review aimed to discuss the potential of these small mol...

In a study carried out at tertiary care hospital we had processed 50 specimens such as operation table (10), sink (9), cheatle forcep fluid (8), thermometer fluid (8), hand wash bowl solution (8), mops (4) and eye drops (3) from various sites in the wards and operation theatres for isolation, identification and antibiotic susceptibility pattern. The specimens were collected after the cleaning a...

Mixed ligand Cu(II) complexes of the type [M(Q)(L)]-2H2O have been synthesized using 8-hydroxyquinoline (HQ) as a primary ligand and N- and/or O-donor amino acids (HL) such as L-threonine, L-proline, L-hydroxyproline, L-isoleucine and L-serine as secondary ligands. The metal complexes have been characterized on the basis of elemental analysis, electrical conductance, room temperature magnetic s...

alpha-Carboxy-3-thienylmethyl penicillin (ticarcillin) is a relatively new semisynthetic penicillin which is more active than carbenillin against Pseudomonas aeruginosa. Among the strains tested, those isolated from the respiratory tract showed an increased susceptibility to carbenicillin and ticarcillin. As with carbenicillin, synergistic activity against P. aeruginosa could be demonstrated wi...

LpxC inhibitors represent a promising class of novel antibiotics selectively combating Gram-negative bacteria. In chiral pool syntheses starting from D- and L-xylose, series four 2r,3c,4t-configured C-furanosidic was obtained. The synthesized hydroxamic acids were tested for antibacterial inhibitory activity, the acquired biological data compared with those previously C-furanosides, molecular d...

Mixed ligand Th(IV) complexes of the type [M(Q)2LNO3.H2O] have been synthesized using 8-hydroxyquinoline (HQ) as a primary ligand and N- and/or O- donor amino acids (HL) such as L-alanine, L-phenylalanine, L-serine and L-tyrosine as secondary ligands. The metal complexes have been characterized on the basis of elemental analysis, electrical conductance, room temperature magnetic susceptibility ...