introduction: preventing and starting early treatment of infections in patients whose immunity system is weak due to malignancies like leukemia can reduce mortality. this study aimed to determine microbial and antibiotic resistance patterns in clinical samples of patients with acute leukemia to start early treatment before the results of clinical tests are known. subjects and methods: in this c...

The aim of this prospective study was to identify possible pathogenic organisms associated with wound complications in the form of wound infections, wound breakdown and the formation of oro-nasal fistulas. The organisms' resistance profile to antibiotics was also evaluated. This prospective study consisted of the evaluation of the intra-oral microbiological profile of 100 babies with soft palat...

The specific activity, substrate profile, response to inhibitors, inducibility, and cellular localization of the beta-lactamase produced by an ampicillin-resistant strain of Haemophilus influenzae type B were investigated. In these properties the enzyme resembles beta-lactamases produced by other gram-negative bacilli more closely than those produced by gram-positive organisms. It is quite simi...

Background: The increase of antimicrobial resistance and the scarcity new broad-spectrum antibiotics is a major challenge. Antibiotic cycling one tactic that increases antibiotic homogeneity to greatest extent possible can aid in controlling pattern, but this approach has not undergone thorough evaluation. study’s objective was examine effects an strategy on susceptibility profile by avoiding a...

BACKGROUND Estimating the risk of antibiotic resistance is important in selecting empiric antibiotics. We asked how the timing, number of courses, and duration of antibiotic therapy in the previous 3 months affected antibiotic resistance in isolates causing invasive pneumococcal disease (IPD). METHODS We conducted prospective surveillance for IPD in Toronto, Canada, from 2002 to 2011. Antimic...

BACKGROUND In this study a large random collection (n=2188) of facultative oligotrophic bacteria, from 90 water samples gathered in three consecutive years (2007-2009) from three different sampling sites of River Mahananda in Siliguri, West Bengal, India, were investigated for the presence of class 1 integrons and sequences of the amplification products. METHODOLOGY/PRINCIPAL FINDINGS Replica...

The study reported the molecular characterization, antibiotic susceptibility profile and nature of resistance genes in multiple resistant Pseudomonas aeruginosa isolated from selected hospital fomites hands health care workers Ondo, Nigeria. Various were swabbed for detection aeruginosa. Each sample was cultured separately on MacConkey Centrimide agar plates incubated 18-24h at 37oC. Pure isola...

Facklamia species are a rarely reported etiology of clinical infection with few cases described in literature. However, the prevalence of infection may be underestimated due to challenges in species identification. We describe 3 cases of Facklamia species bacteremia and the unique microbiologic aspects inherent to this genus that make it particularly challenging to identify. In addition, given ...

Even though antibiotic eluting bone cements are successfully used in orthopedic practice, adding chemotherapy drugs to bone cement pose a different set of problems. This is mainly due to the toxicity concerns associated with the use of chemotherapy agents. To avoid local or systemic toxicity, the drug elution profile of a particular bone cement/drug concentration need to be determined. The drug...